Structure-activity relationship (SAR) study and design strategies of nitrogen-containing heterocyclic moieties for their anticancer activities

J Akhtar, AA Khan, Z Ali, R Haider, MS Yar - European journal of medicinal …, 2017 - Elsevier
The present review article offers a detailed account of the design strategies employed for the
synthesis of nitrogen-containing anticancer agents. The results of different studies describe …

Imidazoles as potential anticancer agents

I Ali, MN Lone, HY Aboul-Enein - MedChemComm, 2017 - pubs.rsc.org
Cancer is a black spot on the face of humanity in this era of science and technology.
Presently, several classes of anticancer drugs are available in the market, but issues such …

The therapeutic journey of benzimidazoles: A review

Y Bansal, O Silakari - Bioorganic & medicinal chemistry, 2012 - Elsevier
Presence of benzimidazole nucleus in numerous categories of therapeutic agents such as
antimicrobials, antivirals, antiparasites, anticancer, anti-inflammatory, antioxidants, proton …

Structure activity relationship (SAR) study of benzimidazole scaffold for different biological activities: A mini-review

G Yadav, S Ganguly - European journal of medicinal chemistry, 2015 - Elsevier
Benzimidazoles are the fused heterocyclic ring systems which form an integral part of
vitamin B 12 and have been luring many researchers all over the world to assess their …

Anti-cancer nitrogen-containing heterocyclic compounds

Z Hosseinzadeh, A Ramazani… - Current Organic …, 2018 - benthamdirect.com
Cancer is one of the leading causes of death worldwide. Mutation of the cell regulates genes
and protein causing cancer. Surgery, radiotherapy, and the use of anticancer agents are the …

Benzimidazole scaffold as anticancer agent: synthetic approaches and structure–activity relationship

N Shrivastava, MJ Naim, MJ Alam, F Nawaz… - Archiv der …, 2017 - Wiley Online Library
Cancer, also known as malignant neoplasm, is a dreadful disease which involves abnormal
cell growth having the potential to invade or spread to other parts of the body …

[PDF][PDF] Benzimidazole derivatives–an overview

R Walia, M Hedaitullah, SF Naaz… - Int. J. Res. Pharm …, 2011 - cmapspublic3.ihmc.us
Benzimidazole derivatives play important role in medical field with so many
Pharmacological activities such as antimicrobial, antiviral, antidiabetic and anticancer …

Benzimidazole scaffolds as promising antiproliferative agents: A review

S Tahlan, S Kumar, S Kakkar, B Narasimhan - BMC chemistry, 2019 - Springer
Cancer is one of the most serious medical problem and second leading cause of death in
the world, characterized by a deregulation of the cell cycle which mainly results in a …

Benzimidazole: A promising pharmacophore

K Shah, S Chhabra, SK Shrivastava… - Medicinal Chemistry …, 2013 - Springer
The aim of this review is to provide an overview on diverse pharmacological activities of the
benzimidazole moiety. This review highlights recent reports of antimicrobial, anticancer …

Benzimidazole bearing oxadiazole and triazolo-thiadiazoles nucleus: Design and synthesis as anticancer agents

A Husain, M Rashid, R Mishra, S Parveen… - Bioorganic & medicinal …, 2012 - Elsevier
Two new series of benzimidazole bearing oxadiazole [1-(1H-benzo [d] imidazol-2-yl)-3-(5-
substituted-1, 3, 4-oxadiazol-2-yl) propan-1-ones (4a–l)] and triazolo-thiadiazoles [1-(1H …