Current state of potential mechanisms supporting low intensity focused ultrasound for neuromodulation

J Dell'Italia, JL Sanguinetti, MM Monti… - Frontiers in human …, 2022 - frontiersin.org
Low intensity focused ultrasound (LIFU) has been gaining traction as a non-invasive
neuromodulation technology due to its superior spatial specificity relative to transcranial …

[HTML][HTML] Electrophysiological-mechanical coupling in the neuronal membrane and its role in ultrasound neuromodulation and general anaesthesia

A Jerusalem, Z Al-Rekabi, H Chen, A Ercole… - Acta biomaterialia, 2019 - Elsevier
The current understanding of the role of the cell membrane is in a state of flux. Recent
experiments show that conventional models, considering only electrophysiological …

Zero dispersion Kerr solitons in optical microresonators

MH Anderson, W Weng, G Lihachev, A Tikan… - Nature …, 2022 - nature.com
Solitons are shape preserving waveforms that are ubiquitous across nonlinear dynamical
systems from BEC to hydrodynamics, and fall into two separate classes: bright solitons …

[HTML][HTML] Thinking about the nerve impulse: A critical analysis of the electricity-centered conception of nerve excitability

B Drukarch, HA Holland, M Velichkov, JJG Geurts… - Progress in …, 2018 - Elsevier
Nerve impulse generation and propagation are often thought of as solely electrical events.
The prevalence of this view is the result of long and intense study of nerve impulses in …

Computational model of the mechanoelectrophysiological coupling in axons with application to neuromodulation

H Chen, D Garcia-Gonzalez, A Jérusalem - Physical Review E, 2019 - APS
For more than half a century, the action potential (AP) has been considered a purely
electrical phenomenon. However, experimental observations of membrane deformations …

Thinking about the action potential: the nerve signal as a window to the physical principles guiding neuronal excitability

B Drukarch, MMM Wilhelmus - Frontiers in cellular neuroscience, 2023 - frontiersin.org
Ever since the work of Edgar Adrian, the neuronal action potential has been considered as
an electric signal, modeled and interpreted using concepts and theories lent from electronic …

Optical electrophysiology: Toward the goal of label-free voltage imaging

Y Zhou, E Liu, H Muller, B Cui - Journal of the American Chemical …, 2021 - ACS Publications
Measuring and monitoring the electrical signals transmitted between neurons is key to
understanding the communication between neurons that underlies human perception …

Raman scattering: from structural biology to medical applications

AV Vlasov, NL Maliar, SV Bazhenov, EI Nikelshparg… - Crystals, 2020 - mdpi.com
This is a review of relevant Raman spectroscopy (RS) techniques and their use in structural
biology, biophysics, cells, and tissues imaging towards development of various medical …

Acoustic neuromodulation from a basic science prospective

E Sassaroli, N Vykhodtseva - Journal of therapeutic ultrasound, 2016 - Springer
We present here biophysical models to gain deeper insights into how an acoustic stimulus
might influence or modulate neuronal activity. There is clear evidence that neural activity is …

[HTML][HTML] The thermodynamic soliton theory of the nervous impulse and possible medical implications

T Heimburg - Progress in Biophysics and Molecular Biology, 2022 - Elsevier
The textbook picture of nerve activity is that of a propagating voltage pulse driven by
electrical currents through ion channel proteins, which are gated by changes in voltage …