Pathogen recognition by the innate immune system

H Kumar, T Kawai, S Akira - International reviews of immunology, 2011 - Taylor & Francis
Microbial infection initiates complex interactions between the pathogen and the host.
Pathogens express several signature molecules, known as pathogen-associated molecular …

Risk and predictive factors for severe dengue infection: A systematic review and meta-analysis

K Yuan, Y Chen, M Zhong, Y Lin, L Liu - PLoS One, 2022 - journals.plos.org
Background Dengue is a major public health issue worldwide and severe dengue (SD) is
life threatening. It is critical to triage patients with dengue infection in the early stage …

Fc receptors in antibody‐dependent enhancement of viral infections

A Taylor, SS Foo, R Bruzzone, L Vu Dinh… - Immunological …, 2015 - Wiley Online Library
Sensitization of the humoral immune response to invading viruses and production of
antiviral antibodies forms part of the host antiviral repertoire. Paradoxically, for a number of …

Implications of oxidative stress on viral pathogenesis

FC Camini, CC da Silva Caetano, LT Almeida… - Archives of …, 2017 - Springer
Reactive species are frequently formed after viral infections. Antioxidant defences, including
enzymatic and non-enzymatic components, protect against reactive species, but sometimes …

Cellular oxidative stress response controls the antiviral and apoptotic programs in dengue virus-infected dendritic cells

D Olagnier, S Peri, C Steel, N van Montfoort… - PLoS …, 2014 - journals.plos.org
Dengue virus (DENV) is a re-emerging arthropod borne flavivirus that infects more than 300
million people worldwide, leading to 50,000 deaths annually. Because dendritic cells (DC) …

Flaviviridae Viruses and Oxidative Stress: Implications for Viral Pathogenesis

Z Zhang, L Rong, YP Li - Oxidative medicine and cellular …, 2019 - Wiley Online Library
Oxidative stress is induced once the balance of generation and neutralization of reactive
oxygen species (ROS) is broken in the cell, and it plays crucial roles in a variety of natural …

Infection of endothelial cells by dengue virus induces ROS production by different sources affecting virus replication, cellular activation, death and vascular …

LM Meuren, EB Prestes, MP Papa… - Frontiers in …, 2022 - frontiersin.org
Exacerbated inflammatory response and altered vascular function are hallmarks of dengue
disease. Reactive oxygen species (ROS) production has been associated to endothelial …

Dengue virus targets Nrf2 for NS2B3-mediated degradation leading to enhanced oxidative stress and viral replication

M Ferrari, A Zevini, E Palermo, M Muscolini… - Journal of …, 2020 - Am Soc Microbiol
Dengue virus (DENV) is a mosquito-borne virus that infects upward of 300 million people
annually and has the potential to cause fatal hemorrhagic fever and shock. While the …

Dengue epidemics prediction: A survey of the state-of-the-art based on data science processes

P Siriyasatien, S Chadsuthi, K Jampachaisri… - IEEE …, 2018 - ieeexplore.ieee.org
Dengue infection is a mosquitoborne disease caused by dengue viruses, which are carried
by several species of mosquito of the genus Aedes, principally Ae. aegypti. Dengue …

Obesity is positively associated with arachidonic acid-derived 5-and 11-hydroxyeicosatetraenoic acid (HETE)

CA Pickens, LM Sordillo, C Zhang, JI Fenton - Metabolism, 2017 - Elsevier
Background Oxylipids are oxygenated polyunsaturated fatty acid (PUFA) metabolites that
are responsible for the onset and resolution of the inflammatory response. Enzymatic …