Deep learning assisted surface-enhanced raman spectroscopy (SERS) for rapid and direct nucleic acid amplification and detection: Toward enhanced molecular …

MG Kim, M Jue, KH Lee, EY Lee, Y Roh, M Lee… - ACS …, 2023 - ACS Publications
Surface-enhanced Raman scattering (SERS) has evolved into a robust analytical technique
capable of detecting a variety of biomolecules despite challenges in securing a reliable …

Laser-Shock-Driven In Situ Evolution of Atomic Defect and Piezoelectricity in Graphitic Carbon Nitride for the Ionization in Mass Spectrometry

MJ Kim, JY Noh, TG Yun, MJ Kang, DH Son, JC Pyun - ACS nano, 2022 - ACS Publications
Nanostructures─ coupled with mass spectrometry─ have been intensively investigated to
improve the detection sensitivity and reproducibility of small biomolecules in laser …

Automated sample-to-answer system for rapid and accurate diagnosis of emerging infectious diseases

B Koo, MG Kim, K Lee, JY Kim, S Lee, SH Kim… - Sensors and Actuators B …, 2023 - Elsevier
Automated sample-to-answer systems that promptly diagnose emerging infectious diseases,
such as zoonotic diseases, are crucial to preventing the spread of infectious diseases and …

A novel platform using homobifunctional hydrazide for enrichment and isolation of urinary circulating RNAs

B Koo, Y Kim, YO Jang, H Liu, MG Kim… - Bioengineering & …, 2023 - Wiley Online Library
Abstract Changes in specific circulating RNA (circRNA) expressions can serve as diagnostic
noninvasive biomarkers for prostate cancer (PCa). However, there are still unmet needs …

Stabilized Exfoliated Black Phosphorus Nanosheets for Fungal DNA-Extraction Assay

SM Lim, H Liu, MG Kim, EY Lee, HJ Lee, Y Roh, M Lee… - BioChip Journal, 2024 - Springer
DNA extraction is essential in fields like medicine, biotechnology, and environmental
science. Traditional DNA-extraction methods often face challenges, especially with …

Multicenter Testing of a Simple Molecular Diagnostic System for the Diagnosis of Mycobacterium Tuberculosis

HJ Lee, NH Kim, EH Lee, YS Yoon, YJ Jeong, BC Lee… - Biosensors, 2023 - mdpi.com
Mycobacterium tuberculosis (MTB) is a communicable disease and still remains a threat to
common health. Thus, early diagnosis and treatment are required to prevent the spread of …

Hot-Spot-Specific Probe (HSSP) for Rapid and Accurate Detection of KRAS Mutations in Colorectal Cancer

HJ Lee, B Koo, YO Jang, H Liu, TNT Dao, SB Lim… - Biosensors, 2022 - mdpi.com
Detection of oncogene mutations has significance for early diagnosis, customized treatment,
treatment progression, and drug resistance monitoring. Here, we introduce a rapid …

Self-directed molecular diagnostics (SdMDx) system for COVID-19 via one-pot processing

YO Jang, NH Kim, Y Roh, B Koo, HJ Lee, JY Kim… - Sensors and Actuators B …, 2023 - Elsevier
Rapid, sensitive, and specific detection of the severe acute respiratory syndrome
coronavirus (SARS-CoV)− 2 during early infection is pivotal in controlling the spread and …