In vivo tau PET imaging in dementia: pathophysiology, radiotracer quantification, and a systematic review of clinical findings
In addition to the deposition of β-amyloid plaques, neurofibrillary tangles composed of
aggregated hyperphosphorylated tau are one of the pathological hallmarks of Alzheimer's …
aggregated hyperphosphorylated tau are one of the pathological hallmarks of Alzheimer's …
Association of apolipoprotein E genetic variation in Alzheimer's disease in Indian population: a meta-analysis
R Agarwal, CB Tripathi - American Journal of Alzheimer's …, 2014 - journals.sagepub.com
Background: Dementia is an age-related disorder associated with elderly population,
resulting from interaction of lifestyle risk factors with genetic, vascular, and other risk factors …
resulting from interaction of lifestyle risk factors with genetic, vascular, and other risk factors …
Associations between plasma biomarkers and cognition in patients with Alzheimer's disease and amnestic mild cognitive impairment: a cross-sectional and …
Brain degeneration in patients with Alzheimer's disease (AD) results from the accumulation
of pathological amyloid-β (Aβ) plaques and tau protein tangles, leading to altered plasma …
of pathological amyloid-β (Aβ) plaques and tau protein tangles, leading to altered plasma …
Malignant brain aging: the formidable link between dysregulated signaling through mechanistic target of rapamycin pathways and alzheimer's disease (type 3 …
SM de la Monte - Journal of Alzheimer's Disease, 2023 - content.iospress.com
Malignant brain aging corresponds to accelerated age-related declines in brain functions
eventually derailing the self-sustaining forces that govern independent vitality. Malignant …
eventually derailing the self-sustaining forces that govern independent vitality. Malignant …
A systematic review and meta-analysis of plasma amyloid 1-42 and tau as biomarkers for Alzheimer's disease
KB Shanthi, S Krishnan, P Rani - SAGE open medicine, 2015 - journals.sagepub.com
Objective: Amyloid 1-42 (Aβ42) and tau in cerebrospinal fluid are currently used as markers
for diagnosis of Alzheimer's disease. Conflicting reports exist regarding their plasma levels …
for diagnosis of Alzheimer's disease. Conflicting reports exist regarding their plasma levels …
Numerical simulations reveal randomness of Cu (II) induced Aβ peptide dimerization under conditions present in glutamatergic synapses
The interactions between the Aβ1–40 molecules species and the copper ions (Cu (II)) were
intensively investigated due to their potential role in the development of the Alzheimer …
intensively investigated due to their potential role in the development of the Alzheimer …
Early-Stage Moderate Alcohol Feeding Dysregulates Insulin-Related Metabolic Hormone Expression in the Brain: Potential Links to Neurodegeneration Including …
Y Yang, M Tong… - Journal of Alzheimer's …, 2024 - journals.sagepub.com
Background: Alzheimer's disease (AD), one of the most prevalent causes of dementia, is
mainly sporadic in occurrence but driven by aging and other cofactors. Studies suggest that …
mainly sporadic in occurrence but driven by aging and other cofactors. Studies suggest that …
Immunomagnetic Reduction Detects Plasma Aβ1–42 Levels as a Potential Dominant Indicator Predicting Cognitive Decline
SY Yang, HC Liu, WP Chen - Neurology and Therapy, 2020 - Springer
Although the concentrations of Alzheimer's disease (AD) biomarkers Aβ 1–40, Aβ 1–42 and
tau protein are very low in human plasma, ultrasensitive assays such as immunomagnetic …
tau protein are very low in human plasma, ultrasensitive assays such as immunomagnetic …
[HTML][HTML] Analysis of apolipoprotein E genetic variation in patients with Alzheimer disease referred to Imam Reza Clinic, Rasht, Iran, in 2015
AR Ghayeghran, M Akbarshahi, Z Salehi… - Iranian Journal of …, 2017 - ncbi.nlm.nih.gov
Background: Alzheimer disease (AD) is a progressive neurological degenerative disorder
and the most common form of dementia. There are about 100 genes linked to AD including …
and the most common form of dementia. There are about 100 genes linked to AD including …