Abstract Beta-2-Glycoprotein I (β2GPI) plays a number of essential roles throughout the
body. β2GPI, C-reactive protein and thrombomodulin are the only three proteins that …

Antiphospholipid antibodies (aPL) can be detected by functional (lupus anticoagulant)
and/or by solid phase assays (anti-cardiolipin and anti-beta2 glycoprotein I). Although …

Tripodi A, de Groot PG, Pengo V (IRCCS Cà Granda Ospedale Maggiore Policlinico
Foundation and Università degli Studi di Milano, Milan, Italy; Utrecht University Medical …

Abstract β2-Glycoprotein I (β2GPI) is an evolutionary conserved, abundant circulating
protein. Although its function remains uncertain, accumulated evidence points toward …

Summary Background: β 2‐Glycoprotein I (β 2 GPI) is an abundant plasma protein that is
closely linked to blood clotting, as it interacts with various protein and cellular components of …

Antiphospholipid syndrome is a systemic autoimmune disease associated with thrombosis
and recurrent fetal loss in the setting of detectable antiphospholipid (aPL) antibodies. The …

Antiphospholipid syndrome (APS), also known as Hughes Syndrome, is a systemic
autoimmune disease characterized by thrombosis and/or pregnancy morbidity in the …

The antiphospholipid syndrome (APS) is diagnosed by the combination of vascular
thrombosis and/or pregnancy morbidity and the detection of antiphospholipid antibodies …

Cerebral and cardiovascular ischaemic events are frequent complications of SLE and
constitute primary causes of permanent damage. However, the pathogenic determinants of …

The relationship between autoimmunity and reproduction has long been recognized. This
relationship is bidirectional and includes many diverse issues, but in this review article, we …