The incidence of breast cancer ranks first among female malignant tumors that affect
women's health. Epidermal growth factor receptor (EGFR) family overexpression, especially …

One of the primary functions of the intestinal epithelium is to transport fluid and electrolytes
to and from the luminal contents. Under normal circumstances, absorptive and secretory …

Cholera is a global health problem with no targeted therapies. The Ca2+-sensing receptor
(CaSR) is a regulator of intestinal ion transport and a therapeutic target for diarrhea, and …

Small molecule receptor tyrosine kinase inhibitors (SM-TKIs) are among a group of targeted
cancer therapies, intended to be more specific to cancer cells compared with treatments …

Background Preclinical cell-based assays that recapitulate human disease play an
important role in drug repurposing. We previously developed a functional forskolin induced …

Background: Potential novel strategies for adverse event (AE) management of osimertinib
therapy, including therapeutic drug monitoring and the use of biomarkers, have not yet been …

Chloride transport across cell membranes is broadly involved in epithelial fluid transport, cell
volume and pH regulation, muscle contraction, membrane excitability, and organellar …

The identification of Epidermal Growth Factor Receptor (EGFR) mutations in lung
adenocarcinoma has facilitated the development of personalized medicine based on …

Abstract Ethnopharmacological relevance Resina Draconis (RD) is the red resin of
Dracaena cochinchinensis (Lour.) SC Chen and most used as a hemostatic drug in …

Epidermal growth factor receptor tyrosine kinase inhibitors (EGFr TKIs) are first‐line
therapies for various cancers, and cause dose‐limiting severe diarrhea in many patients. We …