Advances in the treatment, diagnosis, control and scientific understanding of taeniid cestode parasite infections over the past 50 years

MW Lightowlers, RB Gasser, A Hemphill… - International journal for …, 2021 - Elsevier
In the past 50 years, enormous progress has been made in the diagnosis, treatment and
control of taeniid cestode infections/diseases and in the scientific understanding thereof …

Taenia solium taeniasis/cysticercosis: From parasite biology and immunology to diagnosis and control

MA Dixon, P Winskill, WE Harrison… - Advances in Parasitology, 2021 - Elsevier
Infection with the pork tapeworm (Taenia solium) is responsible for a substantial global
burden of disease, not only restricted to its impact on human health, but also resulting in a …

Control of Taenia solium taeniasis/cysticercosis: The best way forward for sub-Saharan Africa?

S Gabriël, P Dorny, KE Mwape, C Trevisan, UC Braae… - Acta tropica, 2017 - Elsevier
Taenia solium taeniasis/cysticercosis is a neglected parasitic zoonosis with significant
economic and public health impacts. Control measures can be broadly grouped into …

Control of Taenia solium taeniasis/cysticercosis: past practices and new possibilities

MW Lightowlers - Parasitology, 2013 - cambridge.org
Neurocysticercosis continues to be a major health burden on humans living in many regions
of the world, despite the availability of highly effective taeniacides and identification of the …

Designing a minimal intervention strategy to control Taenia solium

MW Lightowlers, M Donadeu - Trends in parasitology, 2017 - cell.com
Neurocysticercosis is an important cause of epilepsy in many developing countries. The
disease is a zoonosis caused by the cestode parasite Taenia solium. Many potential …

Implementation of a practical and effective pilot intervention against transmission of Taenia solium by pigs in the Banke district of Nepal

I Poudel, K Sah, S Subedi, D Kumar Singh… - PLoS neglected …, 2019 - journals.plos.org
Taenia solium is a zoonotic cestode parasite which causes human neurocysticercosis. Pigs
transmit the parasite by acting as the intermediate host. An intervention was implemented to …

Pharmacokinetics, safety, and tolerability of oxfendazole in healthy volunteers: a randomized, placebo-controlled first-in-human single-dose escalation study

G An, DJ Murry, K Gajurel, T Bach, G Deye… - Antimicrobial agents …, 2019 - Am Soc Microbiol
Cysticercosis is a parasitic disease that frequently involves the human central nervous
system (CNS), and current treatment options are limited. Oxfendazole, a veterinary medicine …

Pharmacokinetics, safety, and tolerability of oxfendazole in healthy adults in an open-label phase 1 multiple ascending dose and food effect study

T Bach, S Galbiati, JK Kennedy, G Deye… - Antimicrobial agents …, 2020 - Am Soc Microbiol
Neurocysticercosis and trichuriasis are difficult-to-treat parasitic infections that affect more
than 1.5 billion people worldwide. Oxfendazole, a potent broad-spectrum benzimidazole …

Oxfendazole: a promising agent for the treatment and control of helminth infections in humans

AE Gonzalez, EE Codd, J Horton… - Expert review of anti …, 2019 - Taylor & Francis
ABSTRACT Introduction: Oxfendazole (methyl [5-(phenylsulphinyl)-1H benzimidazole-2-yl]
carbamate) has a particularly long metabolic half-life in ruminants, and its metabolite …

[HTML][HTML] Assessing the impact of a joint human-porcine intervention package for Taenia solium control: Results of a pilot study from northern Lao PDR

AL Okello, L Thomas, P Inthavong, A Ash, B Khamlome… - Acta tropica, 2016 - Elsevier
Following confirmation that a remote village of approximately 300 inhabitants in northern
Lao PDR was hyperendemic for the Neglected Tropical Disease Taenia solium, a pilot …