Yeasts, such as Saccharomyces cerevisiae, have long served as useful models for the study
of oxidative stress, an event associated with cell death and severe human pathologies. This …

Neuronal ceroid lipofuscinoses (NCL) comprise a group of inherited lysosomal disorders
with variable age of onset, characterized by lysosomal accumulation of autofluorescent …

Yeast cells are challenged by various environmental stresses in the process of industrial
fermentation. As the currently main organism for bio-ethanol production, Saccharomyces …

In response to environmental stress, microorganisms adapt to drastic changes while
exerting cellular functions by controlling gene expression, metabolic pathways, enzyme …

Nitric oxide (NO) is a small molecule with distinct roles in diverse physiological functions in
biological systems, among them the control of the apoptotic signalling cascade. By …

Neuronal ceroid lipofuscinoses are a group of fatal progressive neurodegenerative diseases
predominantly affecting children. Identification of mutations that cause neuronal ceroid …

Mitocurcumin (a triphenylphosphonium curcumin derivative) was previously reported as a
selective antitumoral compound on different cellular lines, as well as a potent bactericidal …

The neuronal ceroid lipofuscinoses (NCLs, Batten disease) are a group of inherited
childhood‐onset neurodegenerative disorders characterized by the lysosomal accumulation …

Aging is a multifactorial process determined by molecular, cellular and systemic factors and
it is well established that advancing age is a leading risk factor for several …

Candidaalbicans, an opportunistic pathogen, can undergo programmed cell death upon
various stimuli, including oxidative stress. In this study, we showed that deletion of CaMCA1 …