The solute carrier 18B1 (SLC18B1) is the most recently identified gene of the vesicular
amine transporter family and is conserved in the animal kingdom from insects to humans …

Introduction: Despite more than 30 years of research on p53 resulting in> 50,000
publications, we are now beginning to figure out the complexity of the p53 pathway, gene …

PIK3CA is a key component of phosphatidylinositol 3-kinase (PI3K) pathway that its
involvement in tumorigenesis has been revealed by previous research. However, its …

Bladder cancer (BCa) remains a significant source of morbidity and mortality. BCa is one of
the most expensive tumors to treat, in part because of a lack of nonsurgical options. The …

Cancer chemopreventive agents inhibit the formation of precursor lesions and/or the
progression of these lesions to late stage disease. This approach to disease control has the …

Lung cancer is the leading cause of cancer deaths worldwide. Targeting complementary
pathways will achieve better treatment efficacy than a single agent high-dose strategy that …

Objectives The aim of this study is to identify the clinical tumor stage related mRNAs and
miRNAs, shedding light on the potential molecular mechanisms of cervical squamous cell …

Introduction: Urinary bladder cancer (UBC) is the second most frequent malignancy of the
urinary system and the ninth most common cancer worldwide, affecting individuals over the …

Daily dosing of either NSAIDs or EGFR inhibitors has been shown to prevent bladder cancer
development in a N-butyl-(4-hydroxybutyl) nitrosamine (OH-BBN)-induced rat model …

We have developed a murine intravesical orthotopic human bladder cancer (mio-hBC)
model for the establishment of superficial urothelial cell carcinomas. In this model we …