Retroviruses exclusively infect vertebrates, causing a variety of diseases. The replication of
retroviruses requires reverse transcription and integration into host genomes. When …

Amphibians and non-avian reptiles represent a significant proportion of terrestrial
vertebrates, however knowledge of their viruses is not proportional to their abundance …

Foamy viruses (FVs) are an ancient lineage of retroviruses, with an evolutionary history
spanning over 450 million years. Vector systems based on Prototype Foamy Virus (PFV) are …

Non-human primates (NHP) are an important source of viruses that can spillover to humans
and, after adaptation, spread through the host population. Whereas HIV-1 and HTLV-1 …

Tuatara (Sphenodon punctatus) are one of the most phylogenetically isolated vertebrate
species and provide a unique host system to study virus evolution. While the tuatara …

The development of high-throughput sequencing (HTS) technologies and metagenomics
protocols deeply impacted the discovery of viral diversity. Moreover, the characterization of …

In a previous study, a metatranscriptomics survey of RNA viruses in several important lower
vertebrate host groups revealed huge viral diversity, transforming the understanding of the …

Emerging viral outbreaks resulting from host switching is an area of continued scientific
interest. Such events can result in disease epidemics or in some cases, clinically silent …

ABSTRACT SERINC5 restricts nef-defective HIV-1 by affecting early steps of the virus life
cycle. Distantly related retroviruses with a wide host range encode virulent factors in …

Foamy viruses (FVs) are complex retroviruses that can infect humans and other animals. In
this study, by integrating transcriptomic and genomic data, we discovered 412 FVs from 6 …