Background Methotrexate is considered the preferred disease‐modifying anti‐rheumatic
drug (DMARD) for the treatment of rheumatoid arthritis, but controversy exists on the …

Summary Abstract Sulfasalazine (salazosulfapyridine)[Azulfidine®, Salazopyrin®] is a well
established disease-modifying antirheumatic drug (DMARD) used in the treatment of …

Rheumatoid arthritis (RA) is an autoimmune disease with an unclear pathogenic
mechanism. However, it has been proven that the key underlying risk factor is a genetic …

Objectives To assess the efficacy and safety of synthetic disease-modifying antirheumatic
drugs (DMARDs) in adults with rheumatoid arthritis (RA)—a first step in a European League …

A variety of disease-modifying antirheumatic drugs (DMARDs) are available to control the
clinical activity of rheumatoid arthritis (RA). Methotrexate (MTX), an analogue of folic acid …

Rheumatoid arthritis is a common autoimmune disease primarily manifesting as chronic
synovitis, subsequently leading to a change in joint integrity. Progressive disability and …

Objectives To perform a systematic literature review of effective strategies for the treatment of
rheumatoid arthritis (RA). Methods As part of a European League Against Rheumatism …

Highlights•Elucidation of the intricate mechanism involved in the pathogenesis of
rheumatoid arthritis.•Combination delivery in clinical trials and preclinical models.•Topical …

Background: Multiple sclerosis (MS) shares many pathologic features with other immune-
mediated inflammatory diseases, such as rheumatoid arthritis, Crohn disease, and psoriasis …

Objective For patients with rheumatoid arthritis (RA) in remission who are receiving disease‐
modifying antirheumatic drugs (DMARDs), radiographic progression correlates with imaging …