Polyhydroxyalkanoates (PHA) are microbial polyesters produced by numerous prokaryotes.
These materials are generally considered to be renewable and biodegradable alternatives …

The current problems with increasing bacterial resistance to antibacterial therapies, resulting
in a growing frequency of incurable bacterial infections, necessitates the acceleration of …

INTRODUCTION Vertebrate development comprises multiple complex morphogenetic
processes that shape the embryonic body plan through self-organization of pluripotent stem …

Physical exercise can improve brain function and delay neurodegeneration; however, the
initial signal from muscle to brain is unknown. Here we show that the lactate receptor …

The expression of short-chain fatty acid receptors GPR41/FFAR3 and GPR43/free fatty acid
receptor 2 (FFAR2) was studied in the gastrointestinal tract of transgenic monomeric red …

CRISPR base editing is a powerful method to engineer bacterial genomes. However, it
restricts editing to single-nucleotide substitutions. Here, to address this challenge, we adapt …

Major histocompatibility complex E (MHC-E) is a highly conserved, ubiquitously expressed,
nonclassical MHC class Ib molecule with limited polymorphism that is primarily involved in …

Genetic humanization, which involves replacing mouse genes with their human
counterparts, can create powerful animal models for the study of human genes and …

The mammalian central nervous system (CNS) contains a remarkable array of neural cells,
each with a complex pattern of connections that together generate perceptions and higher …

A recombination system has been developed for efficient chromosome engineering in
Escherichia coli by using electroporated linear DNA. A defective λ prophage supplies …