Current concepts and challenges in the treatment of cleft lip and palate patients—A comprehensive review

A Paradowska-Stolarz, M Mikulewicz… - Journal of Personalized …, 2022 - mdpi.com
Cleft lip and cleft palate has one of the highest incidences in the malformations of the oral
cavity, that varies between populations. The background underlying the issue of cleft lip and …

Characterizing the microbiota of cleft lip and palate patients: a comprehensive review

E Gershater, Y Liu, B Xue, MK Shin, H Koo… - Frontiers in cellular …, 2023 - frontiersin.org
Orofacial cleft disorders, including cleft lip and/or palate (CL/P), are one of the most
frequently-occurring congenital disorders worldwide. The health issues of patients with CL/P …

Surgical reconstruction of craniofacial malformations

MA Carro, G Donofrio, E Tokgöz - … facial plastic surgery: A review of …, 2023 - Springer
Craniofacial anomalies contribute to one third of all congenital deformities, and are often
observed with syndromic genetic conditions such as Crouzon or Treacher-Collins syndrome …

Whole-genome sequencing reveals de-novo mutations associated with nonsyndromic cleft lip/palate

W Awotoye, PA Mossey, JB Hetmanski, LJJ Gowans… - Scientific reports, 2022 - nature.com
Abstract The majority (85%) of nonsyndromic cleft lip with or without cleft palate (nsCL/P)
cases occur sporadically, suggesting a role for de novo mutations (DNMs) in the etiology of …

Prevalence, trend, and associated risk factors for cleft lip with/without cleft palate: a national study on live births from 2016 to 2021

MH Heydari, A Sadeghian, G Khadivi, HJ Mustafa… - BMC Oral Health, 2024 - Springer
Backgrounds Cleft lip with or without cleft palate (CL/P) is the most common congenital
craniofacial anomaly, including non-syndromic cleft lip with or without cleft palate and cleft …

Single cell sequencing of the mouse anterior palate reveals mesenchymal heterogeneity

YH Ozekin, R O'Rourke, EA Bates - Developmental Dynamics, 2023 - Wiley Online Library
Background Cleft palate is one of the most prevalent birth defects. Mice are useful for
studying palate development because of their morphological and genetic similarities to …

Trends of cleft surgeries and predictors of late primary surgery among children with cleft lip and palate at the University College Hospital, Nigeria: A retrospective …

AI Michael, G Olorunfemi, A Olusanya, O Oluwatosin - Plos one, 2023 - journals.plos.org
Background Cleft of the lip and palate is the most common craniofacial birth defect with a
worldwide incidence of one in 700 live births. Early surgical repairs are aimed at improving …

Current applications of artificial intelligence in cleft care: a scoping review

H Dhillon, PK Chaudhari, K Dhingra, RF Kuo… - Frontiers in …, 2021 - frontiersin.org
Objective: This scoping review aims to identify the various areas and current status of the
application of artificial intelligence (AI) for aiding individuals with cleft lip and/or palate …

Obturator manufacturing for oronasal fistula after cleft palate repair: a review from handicraft to the application of digital techniques

J Chen, R Yang, B Shi, Y Xu, H Huang - Journal of Functional …, 2022 - mdpi.com
An oronasal fistula (ONF) is an abnormal structure between the oral and nasal cavities,
which is a common complication of cleft palate repair due to the failure of wound healing …

Rethinking the rule of 10s: early cleft lip repair improves weight gain

K Kondra, E Stanton, C Jimenez… - The Cleft Palate …, 2023 - journals.sagepub.com
Objective This study compares patients undergoing early cleft lip repair (ECLR)(< 3-months)
and traditional lip repair (TLR)(3-6 months) with/without nasoalveolar molding (NAM) to …