Phthalic anhydride (PA): a valuable substrate in organic transformations

K Nikoofar, M Sadathosainy - RSC advances, 2023 - pubs.rsc.org
This review has been centralized on applications of phthalic anhydride (PA) as a valuable
and significant heterocyclic substrate in two-and multicomponent organic reactions. The …

Vision on Synthetic and Medicinal Facets of 1,2,4-Triazolo[3,4-b][1,3,4]thiadiazine Scaffold

R Aggarwal, M Hooda, P Kumar, G Sumran - Topics in Current Chemistry, 2022 - Springer
The present review article strives to compile the latest synthetic approaches for the synthesis
of triazolothiadiazine and its derivatives, along with their diverse pharmacological activities …

Microwave irradiated one pot, three component synthesis of a new series of hybrid coumarin based thiazoles: Antibacterial evaluation and molecular docking studies

S Mamidala, SR Peddi, RK Aravilli, PC Jilloju… - Journal of Molecular …, 2021 - Elsevier
A series of new coumarin based thiazoles were synthesized by the microwave irradiation of
thiocarbohydrazide, aldehydes and 3-(2-bromoacetyl) coumarins. Structures of all the …

A facile one-pot, three component synthesis of a new series of 1, 3, 4-thiadiazines: Anticancer evaluation and molecular docking studies

S Mamidala, V Vangala, SR Peddi… - Journal of Molecular …, 2021 - Elsevier
Abstract A series of new 1, 3, 4-thiadiazines were synthesized by the conventional method of
dehydroacetic acid, thiocarbohydrazide and substituted phenacyl bromides or substituted 3 …

Synthesis and antimicrobial activities of some new bis (Schiff Bases) and their triazole-based lariat macrocycles

RM Kassab, FSAM Khalil, AA Abbas - Polycyclic Aromatic …, 2022 - Taylor & Francis
New series of bis (amino-1, 2, 4-triazoles‏) 5a–f were prepared by the reaction of bis (chloro)
diamides 3a–d with 5-substituted-4-amino-1, 2, 4-triazoles-3-thiole (4a–c). Reaction of bis …

Structural elucidation and in-silico evaluation of 1, 2, 4-triazole derivative as potent Omicron variant of SARS-CoV-2 spike protein inhibitor with pharmacokinetics …

DCV Kumar, BS Chethan, V Shalini… - Journal of Molecular …, 2024 - Elsevier
One of the most significant issues in contemporary medicine and pharmacy is the search for
powerful bioactive, efficient, low-toxic anti-COVID agents. In this contrast, present work …

Synthetic utility of aminomercapto [1, 2, 4] triazoles in the preparation of fused triazoles

SM Riyadh, TZ Abolibda, AR Sayed… - Current Organic …, 2022 - ingentaconnect.com
Triazoles and their fused derivatives are regarded as one of the most pharmacologically
significant pillars due to their potent, broad, and numerous activities. This current review …

Design and synthesis of new thiazoles by microwave-assisted method: evaluation as an anti-breast cancer agents and molecular docking studies

S Mamidala, VS Mudigunda, SR Peddi… - Synthetic …, 2020 - Taylor & Francis
A series of novel thiazole analogues were designed and synthesized by the microwave-
assisted multicomponent reaction of thiocarbohydrazide, aldehydes with substituted …

Highly Luminescent 4H-1,2,4-Triazole Derivatives: Synthesis, Molecular Structure and Photophysical Properties

M Olesiejuk, A Kudelko, M Świątkowski - Materials, 2020 - mdpi.com
An alternative approach to the Suzuki cross-coupling reaction is used to synthesize a series
of new luminophores based on 4-alkyl-4 H-1, 2, 4-triazole cores conjugated via 1, 4 …

Characterization and molecular docking studies of substituted 3-(2-benzylidenehydrazinyl)-6-phenyl-7H-[1, 2, 4] triazolo [3, 4-b][1, 3, 4] thiadiazines synthesized via a …

SC Jilloju, PC Jilloju, M Jatavath, MA Rao - Journal of Molecular Structure, 2021 - Elsevier
Abstract A series of 3-(2-benzylidenehydrazinyl)-6-phenyl-7H-[1, 2, 4] triazolo [3, 4-b][1, 3, 4]
thiadiazines were synthesized via a one-pot, three-component protocol. The new derivatives …