Members of the coronaviridae family are endemic to human populations and have caused
several epidemics and pandemics in recent history. In this review, we will discuss the …

The present use of mRNA vaccines against COVID-19 has shown for the first time the
potential of mRNA vaccines for infectious diseases. Here we will summarize the current …

Although Rhinolophus bats harbor diverse clade 3 sarbecoviruses, the structural
determinants of receptor tropism along with the antigenicity of their spike (S) glycoproteins …

Abstract Ever-evolving SARS-CoV-2 variants of concern (VOCs) have diminished the
effectiveness of therapeutic antibodies and vaccines. Developing a coronavirus vaccine that …

BACKGROUND There is uncertainty about the timing of booster vaccination against COVID-
19 in highly vaccinated populations during the present endemic phase of COVID-19. Studies …

Evolution of SARS-CoV-2 alters the antigenicity of the immunodominant spike (S) receptor-
binding domain and N-terminal domain, undermining the efficacy of vaccines and antibody …

Circulating bat coronaviruses represent a pandemic threat. However, our understanding of
bat coronavirus pathogenesis and transmission potential is limited by the lack of …

Antibodies perform both neutralizing and non-neutralizing effector functions that protect
against certain pathogen-induced diseases. A human antibody directed at the SARS-CoV-2 …

Abstract Immunizing mice with Crimean-Congo hemorrhagic fever virus (CCHFV)
nucleoprotein (NP), glycoprotein precursor (GPC), or with the GP38 domain of GPC, can be …

The function of the spike protein N terminal domain (NTD) in coronavirus (CoV) infections is
poorly understood. However, some rare antibodies that target the SARS-CoV-2 NTD …