Dental agenesis: genetic and clinical perspectives

PJ De Coster, LA Marks, LC Martens… - Journal of Oral …, 2009 - Wiley Online Library
Dental agenesis is the most common developmental anomaly in humans and is frequently
associated with several other oral abnormalities. Whereas the incidence of missing teeth …

Genetic basis of non-syndromic anomalies of human tooth number

G Galluccio, M Castellano, C La Monaca - Archives of Oral Biology, 2012 - Elsevier
Teeth organogenesis develops through a well-ordered series of inductive events involving
genes and BMP, FGF, SHH and WNT represent the main signalling pathways that regulate …

Genetic basis of tooth agenesis

P Nieminen - Journal of Experimental Zoology Part B …, 2009 - Wiley Online Library
Tooth agenesis or hypodontia, failure to develop all normally developing teeth, is one of the
most common developmental anomalies in man. Common forms, including third molar …

[PDF][PDF] Clinical genetic basis of tooth agenesis

M Abu-Hussein, N Watted, M Yehia, P Proff… - Journal of Dental and …, 2015 - aaup.edu
Tooth agenesis is one of the most common congenital malformations in humans.
Hypodontia can either occur as an isolated condition (non-syndromic hypodontia) or can be …

PAX9 gene mutations and tooth agenesis: A review

O Bonczek, VJ Balcar, O Šerý - Clinical genetics, 2017 - Wiley Online Library
Paired box 9 (PAX9) is one of the best‐known transcription factors involved in the
development of human dentition. Mutations in PAX9 gene could, therefore, seriously …

Patterns of dental agenesis highlight the nature of the causative mutated genes

BP Fournier, MH Bruneau, S Toupenay… - Journal of dental …, 2018 - journals.sagepub.com
The most common outcome of defective dental morphogenesis in human patients is dental
agenesis (absence of teeth). This may affect either the primary or permanent dentition and …

Genetic background of nonsyndromic oligodontia: a systematic review and meta-analysis.

S Ruf, D Klimas, M Hönemann… - Journal of Orofacial …, 2013 - search.ebscohost.com
Zusammenfassung Fragestellung Identifizierung aller bekannten Genmutationen, die mit der
Entstehung nonsyndromaler Oligodontien assoziiert werden. Methodik. Eine systematische …

An epidemiological study of dental agenesis in a primary health area in Spain: Estimated prevalence and associated factors

V Tallón-Walton, P Nieminen, S Arte… - … , vol. 15, num. 4, p. 569 …, 2010 - diposit.ub.edu
Objectives: To evaluate the prevalence of dental agenesis and its possible association with
other developmental dental anomalies and systemic entities. Setting and Sample …

[HTML][HTML] Taurodontism in Brazilian patients with tooth agenesis and first and second-degree relatives: A case–control study

RR Gomes, CD Habckost, LG Junqueira, AF Leite… - Archives of oral …, 2012 - Elsevier
AIM: An association between tooth agenesis and taurodontism has been suggested. To
verify if tooth agenesis and taurodontism are associated within families and specific patterns …

Genotype-phenotype pattern analysis of pathogenic PAX9 variants in Chinese Han families with non-syndromic oligodontia

J Ren, S Gan, S Zheng, M Li, Y An, S Yuan, X Gu… - Frontiers in …, 2023 - frontiersin.org
Background: Non-syndromic oligodontia is characterized by the absence of six or more
permanent teeth, excluding third molars, and can have aesthetic, masticatory, and …