Aging is characterized by a gradual decline of the body's biological functions, which can
lead to increased production of reactive oxygen species (ROS). Antioxidants neutralize ROS …

Although the lifetime burden due to mental disorders is increasing, we lack tools for more
precise diagnosing and treating prevalent and disabling disorders such as major depressive …

This study investigates the functional brain network in major depressive disorder using
network theory and a consensus network approach. At the macroscopic level, we found …

Previous studies have shown an association between the thalamocortical dysconnectivity
and treatment-resistant depression (TRD). Whether a single subanesthetic dose of ketamine …

Major depressive disorder (MDD) is characterized by psychomotor retardation whose
underlying neural source remains unclear. Psychomotor retardation may either be related to …

Background Previous neuroimaging has paid little attention to the differences in brain
network integration between patients with treatment-resistant depression (TRD) and non …

Ketamine is a highly effective antidepressant (AD) that targets the glutamatergic system and
exerts profound effects on brain circuits during negative emotional processing. Interestingly …

While there is growing interest in the use of functional magnetic resonance imaging‐
functional connectivity (fMRI‐FC) for biomarker research, low measurement reliability of …

Imaging studies of treatment-resistant depression (TRD) have examined brain activity,
structure, and metabolite concentrations to identify critical areas of investigation in TRD as …

Deep brain stimulation (DBS) of the ventral anterior limb of the internal capsule (vALIC) is a
promising intervention for treatment-resistant depression (TRD). However, the working …