Various pathophysiological mechanisms have been implicated in hypertension, but those
resulting in vascular dysfunction and remodeling are critical and may help to identify critical …

Hypertension is one of the leading risk factors for the development of heart failure. Despite
being a multifactorial disease, in recent years, preclinical and clinical studies suggest strong …

Cardiovascular disease is the leading cause of death in the US and other developed
countries. Metabolic syndrome, including obesity, diabetes/insulin resistance, hypertension …

Myocardial fibrosis is observed in various cardiovascular diseases and plays a key role in
the impairment of cardiac function. Endomyocardial biopsy, as the gold standard for the …

This MiniReview describes the essential biochemical and molecular aspects of matrix
metalloproteinases (MMP s) and briefly discusses how they engage in different diseases …

Background Hyperglycemia and insulin resistance often develop cardiovascular and
nephrological dysfunction in diabetic patients. Sitagliptin is used to treat diabetes and …

Oxidative stress and MMP activity are found in the hearts and arteries in hypertension and
contribute to the resulting hypertrophy and dysfunction. Quercetin is a flavonoid that reduces …

Cardiac muscle is unique because it contracts ceaselessly throughout the life and is highly
resistant to fatigue. The marvelous nature of the cardiac muscle is attributed to its matrix that …

Aims Pregnancy hypertension-induced endothelial dysfunction associated with impairment
of nitric oxide (NO) bioavailability and hemodynamic derangements is a challenging for …

Background and Objective. It has been reported that sodium ferulate (SF) has hematopoietic
function against anemia and immune regulation, inflammatory reaction inhibition, inhibition …