Integrative multi-omics profiling in human decedents receiving pig heart xenografts
In a previous study, heart xenografts from 10-gene-edited pigs transplanted into two human
decedents did not show evidence of acute-onset cellular-or antibody-mediated rejection …
decedents did not show evidence of acute-onset cellular-or antibody-mediated rejection …
Differential gene expression analysis of spatial transcriptomic experiments using spatial mixed models
OE Ospina, AC Soupir, R Manjarres-Betancur… - Scientific Reports, 2024 - nature.com
Spatial transcriptomics (ST) assays represent a revolution in how the architecture of tissues
is studied by allowing for the exploration of cells in their spatial context. A common element …
is studied by allowing for the exploration of cells in their spatial context. A common element …
Integrative multi-omic profiling of two human decedents receiving pig heart xenografts reveals strong perturbations in early immune-cell and cellular metabolism …
Background Recent advances in xenotransplantation in living and decedent humans using
pig xenografts have laid promising groundwork towards future emergency use and first in …
pig xenografts have laid promising groundwork towards future emergency use and first in …