The mechanism underlying extrapulmonary complications of the coronavirus disease 2019 and its therapeutic implication

Q Ning, D Wu, X Wang, D Xi, T Chen, G Chen… - Signal transduction and …, 2022 - nature.com
Abstract The coronavirus disease 2019 (COVID-19) is a highly transmissible disease
caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that poses a …

Role of extracellular vesicles in cell death and inflammation

R Sanwlani, L Gangoda - Cells, 2021 - mdpi.com
Extracellular vesicles (EVs) have been identified as novel mediators of intercellular
communication. They work via delivering the sequestered cargo to cells in the close vicinity …

Proteomic analysis of MSC‐derived apoptotic vesicles identifies Fas inheritance to ameliorate haemophilia a via activating platelet functions

X Zhang, J Tang, X Kou, W Huang… - Journal of …, 2022 - Wiley Online Library
Apoptotic vesicles (apoVs) are apoptotic cell‐derived nanosized vesicles that play a crucial
role in multiple pathophysiological settings. However, their detailed characteristics, specific …

The intersection of obesity and (long) COVID-19: Hypoxia, thrombotic inflammation, and vascular endothelial injury

M Xiang, X Wu, H Jing, VA Novakovic… - Frontiers in cardiovascular …, 2023 - frontiersin.org
The role of hypoxia, vascular endothelial injury, and thrombotic inflammation in worsening
COVID-19 symptoms has been generally recognized. Damaged vascular endothelium plays …

The tricky connection between extracellular vesicles and mitochondria in inflammatory-related diseases

T Di Mambro, G Pellielo, ED Agyapong… - International Journal of …, 2023 - mdpi.com
Mitochondria are organelles present in almost all eukaryotic cells, where they represent the
main site of energy production. Mitochondria are involved in several important cell …

Extracellular vesicles and thrombosis: update on the clinical and experimental evidence

K Zifkos, C Dubois, K Schäfer - International Journal of Molecular …, 2021 - mdpi.com
Extracellular vesicles (EVs) compose a heterogenous group of membrane-derived particles,
including exosomes, microvesicles and apoptotic bodies, which are released into the …

Tissue factor in COVID-19-associated coagulopathy

S Subramaniam, H Kothari, M Bosmann - Thrombosis Research, 2022 - Elsevier
Evidence of micro-and macro-thrombi in the arteries and veins of critically ill COVID-19
patients and in autopsies highlight the occurrence of COVID-19-associated coagulopathy …

Extracellular Vesicle‐Inspired Therapeutic Strategies for the COVID‐19

Z Hu, W Wang, Y Lin, H Guo, Y Chen… - Advanced …, 2024 - Wiley Online Library
Emerging infectious diseases like coronavirus pneumonia (COVID‐19) present significant
challenges to global health, extensively affecting both human society and the economy …

Extracellular vesicles linking inflammation, cancer and thrombotic risks

S Beck, B Hochreiter, JA Schmid - Frontiers in cell and developmental …, 2022 - frontiersin.org
Extracellular vesicles (EVs) being defined as lipid-bilayer encircled particles are released by
almost all known mammalian cell types and represent a heterogenous set of cell fragments …

Surface protein profiling of milk and serum extracellular vesicles unveils body fluid-specific signatures

A Giovanazzi, MJC van Herwijnen, M Kleinjan… - Scientific Reports, 2023 - nature.com
Cell-derived extracellular vesicles (EVs) are currently in the limelight as potential disease
biomarkers. The promise of EV-based liquid biopsy resides in the identification of specific …