Advances and new directions in crystallization control

ZK Nagy, RD Braatz - Annual review of chemical and …, 2012 - annualreviews.org
The academic literature on and industrial practice of control of solution crystallization
processes have seen major advances in the past 15 years that have been enabled by …

Assessment of recent process analytical technology (PAT) trends: a multiauthor review

LL Simon, H Pataki, G Marosi, F Meemken… - … Process Research & …, 2015 - ACS Publications
This multiauthor review article aims to bring readers up to date with some of the current
trends in the field of process analytical technology (PAT) by summarizing each aspect of the …

[HTML][HTML] Progress of pharmaceutical continuous crystallization

D Zhang, S Xu, S Du, J Wang, J Gong - Engineering, 2017 - Elsevier
Crystallization is an important unit operation in the pharmaceutical industry. At present, most
pharmaceutical crystallization processes are performed in batches. However, due to product …

Recent progress in continuous crystallization of pharmaceutical products: precise preparation and control

Y Ma, S Wu, EGJ Macaringue, T Zhang… - … Process Research & …, 2020 - ACS Publications
Crystallization, as a solid–liquid separation process, is employed to purify and isolate a
great diversity of crystalline pharmaceutical products. In recent years, continuous …

Control of polymorphism in continuous crystallization via mixed suspension mixed product removal systems cascade design

TTC Lai, J Cornevin, S Ferguson, N Li… - Crystal Growth & …, 2015 - ACS Publications
Control of polymorphism of the enantiotropic p-aminobenzoic acid at either the α or β
polymorph while maintaining high yield was achieved by mixed suspension mixed product …

Continuous Crystallization and Polymorph Dynamics in the l-Glutamic Acid System

TTC Lai, S Ferguson, L Palmer, BL Trout… - … Process Research & …, 2014 - ACS Publications
Polymorph dynamics of l-glutamic acid were examined during continuous mixed suspension
mixed product removal (MSMPR) crystallization as a function of residence time and …

[图书][B] Control system applications

WS Levine - 1999 - books.google.com
Control technology permeates every aspect of our lives. We rely on them to perform a wide
variety of tasks without giving much thought to the origins of the technology or how it became …

Monitoring and advanced control of crystallization processes

ZK Nagy, M Fujiwara, RD Braatz… - Handbook of Industrial …, 2019 - cambridge.org
Crystallization is one of the main separation and purification processes in the
pharmaceutical, biotechnology, food, microelectronics, fine and bulk chemicals industries …

Mechanisms and control of impurities in continuous crystallization: a review

C Darmali, S Mansouri, N Yazdanpanah… - Industrial & …, 2018 - ACS Publications
Crystallization has been applied to a broad range of industries such as bulk and fine
chemicals and the pharmaceutical and food industries. It is important to strategically control …

Multi-objective optimization based nonlinear model predictive control of seeded cooling crystallization process with application to β form L-glutamic acid

F Sun, T Liu, B Song, Y Cui, ZK Nagy… - Chemical Engineering …, 2024 - Elsevier
For batch performance optimization of seeded cooling crystallization processes with respect
to multiple production objectives, a multi-objective optimization (MOO) based nonlinear …