Longer human lives have led to a global burden of late-life disease. However, some older
people experience little ill health, a trait that should be extended to the general population …

The population of aged individuals is increasing worldwide and this has significant health
and socio-economic implications. Clinical and experimental studies on aging have …

Aging is the major risk factor for many human diseases. In vitro studies have demonstrated
that cellular reprogramming to pluripotency reverses cellular age, but alteration of the aging …

Aging is characterized generally by progressive and overall physiological decline of
functions and is observed in all animals. A long line of evidence has established the …

Sarcopenia is a progressive and widespread skeletal muscle disease that is related to an
increased possibility of adverse consequences such as falls, fractures, physical disabilities …

Mammals differ more than 100-fold in maximum lifespan. Here, we conducted comparative
transcriptomics on 26 species with diverse lifespans. We identified thousands of genes with …

Sweet potatoes are becoming a research focus in recent years due to their unique nutritional
and functional properties. Bioactive carbohydrates, proteins, lipids, carotenoids …

Brain aging is the critical and common factor among several neurodegenerative disorders
and dementia. Cellular, biochemical and molecular studies have shown intimate links …

Immunotherapy is known to be clinically beneficial for cancer patients and in many cases
represents the new standard of care. Because of this success, the interest in integrating …

Accumulating evidence indicates gut microbiota contributes to aging-related disorders.
However, the exact mechanism underlying gut dysbiosis-related pathophysiological …