[HTML][HTML] Diagnostic and therapeutic potential of circulating-free DNA and cell-free RNA in cancer management
Over time, molecular biology and genomics techniques have been developed to speed up
the early diagnosis and clinical management of cancer. These therapies are often most …
the early diagnosis and clinical management of cancer. These therapies are often most …
[HTML][HTML] Protein kinase C (PKC) isozymes as diagnostic and prognostic biomarkers and therapeutic targets for cancer
T Kawano, J Inokuchi, M Eto, M Murata, JH Kang - Cancers, 2022 - mdpi.com
Simple Summary Protein kinase C (PKC) isozymes play key roles in the proliferation,
differentiation, survival, migration, invasion, apoptosis, and anticancer drug resistance of …
differentiation, survival, migration, invasion, apoptosis, and anticancer drug resistance of …
Influence of PRKCE non-synonymous variants on protein dynamics and functionality
Novel protein kinase C (nPKC) family member, protein kinase C epsilon (PKCε) is an AGC
kinase superfamily member. It is associated with neurological and metabolic diseases as …
kinase superfamily member. It is associated with neurological and metabolic diseases as …
[HTML][HTML] Determining KLF14 tertiary structure and diagnostic significance in brain cancer progression
K Zahra, M Shabbir, Y Badshah, JH Trembley… - Scientific Reports, 2022 - nature.com
Expression analysis of new protein targets may play a crucial role in the early detection and
diagnosis of brain tumor progression. The study aimed to investigate the possible relation of …
diagnosis of brain tumor progression. The study aimed to investigate the possible relation of …
Fat mass and obesity associated (FTO)-mediated N6-methyladenosine modification of Krüppel-like factor 3 (KLF3) promotes osteosarcoma progression
HJ Shan, WX Gu, G Duan, HL Chen - Bioengineered, 2022 - Taylor & Francis
ARSTRACT N6-methyladenosine (m6A) methylation is the most common and abundant
methylation modification of eukaryotic mRNAs, which is involved in tumor initiation and …
methylation modification of eukaryotic mRNAs, which is involved in tumor initiation and …
The aged tumor microenvironment limits T cell control of cancer
The etiology and effect of age-related immune dysfunction in cancer is not completely
understood. Here we show that limited priming of CD8+ T cells in the aged tumor …
understood. Here we show that limited priming of CD8+ T cells in the aged tumor …
PRKCE non-coding variants influence on transcription as well as translation of its gene
Untranslated regions of the gene play a crucial role in gene expression regulation at mRNA
and protein levels. Mutations at UTRs impact expression by altering transcription factor …
and protein levels. Mutations at UTRs impact expression by altering transcription factor …
KLF3 Transcription Activates WNT1 and Promotes the Growth and Metastasis of Gastric Cancer via Activation of the WNT/β-Catenin Signaling Pathway
Y Li, Y Wang, Q Zou, S Li, F Zhang - Laboratory Investigation, 2023 - Elsevier
The transcription factor Krüppel-like factor (KLF) 3 is one of the members of the KLF family,
which plays an important role in tumor progression. Nevertheless, the role of KLF3 in the …
which plays an important role in tumor progression. Nevertheless, the role of KLF3 in the …
Oridonin from Rabdosia rubescens: An emerging potential in cancer therapy – A comprehensive review
Cancer incidences are rising each year. In 2020, approximately 20 million new cancer cases
and 10 million cancer‐related deaths were recorded. The World Health Organization (WHO) …
and 10 million cancer‐related deaths were recorded. The World Health Organization (WHO) …
[HTML][HTML] Cross talk of tumor protein D52 (TPD52) with KLF9, PKCε, and MicroRNA 223 in ovarian cancer
Background Gynecologic cancers comprise malignancies in the female reproductive organs.
Ovarian cancer ranks sixth in terms of incidence rates while seventh in terms of mortality …
Ovarian cancer ranks sixth in terms of incidence rates while seventh in terms of mortality …