Allergic rhinitis: a clinical and pathophysiological overview

SM Nur Husna, HTT Tan, N Md Shukri… - Frontiers in …, 2022 - frontiersin.org
Allergic rhinitis (AR) represents a global health concern where it affects approximately 400
million people worldwide. The prevalence of AR has increased over the years along with …

Advances and highlights in allergic rhinitis

Y Zhang, F Lan, L Zhang - Allergy, 2021 - Wiley Online Library
Allergic rhinitis (AR) is a growing public health, medical and economic problem worldwide.
The current review describes the major discoveries related to AR during the past 2 years …

Diversity of macrophages in lung homeostasis and diseases

F Hou, K Xiao, L Tang, L Xie - Frontiers in immunology, 2021 - frontiersin.org
Lung macrophages play important roles in the maintenance of homeostasis, pathogen
clearance and immune regulation. The different types of pulmonary macrophages and their …

Role of IL‐25, IL‐33, and TSLP in triggering united airway diseases toward type 2 inflammation

H Hong, S Liao, F Chen, Q Yang, DY Wang - Allergy, 2020 - Wiley Online Library
Under the concept of" united airway diseases," the airway is a single organ wherein upper
and lower airway diseases are commonly comorbid. The upper and lower airways are lined …

Mechanisms of allergen-specific immunotherapy and allergen tolerance

UC Kucuksezer, C Ozdemir, L Cevhertas… - Allergology …, 2020 - jstage.jst.go.jp
abstract Allergen-specific immunotherapy (AIT) is the mainstay treatment for the cure of
allergic disorders, with depicted efficacy and safety by several trials and meta-analysis. AIT …

M2 macrophages upregulated by allergen exposure in seasonal allergic rhinitis

H Lou, Y Huang, X Chu, Y Wang, C Wang… - International Archives of …, 2023 - karger.com
Introduction: Macrophages play a central role in balancing the immune response by
switching phenotypes between the M1 and M2 profiles according to a delicate equilibrium …

Overexpression of miR-4669 enhances tumor aggressiveness and generates an immunosuppressive tumor microenvironment in hepatocellular carcinoma: its clinical …

T Nakano, CL Chen, IH Chen, HP Tseng… - International Journal of …, 2023 - mdpi.com
Accumulating evidence suggests the involvement of tumor-derived exosomes in the
development and recurrence of hepatocellular carcinoma (HCC). We previously identified …

The pathogenesis of food allergy and protection offered by dietary compounds from the perspective of epigenetics

F Yang, X Zhang, Y Xie, J Yuan, J Gao, H Chen… - The Journal of Nutritional …, 2024 - Elsevier
Food allergy is a global food safety concern, with an increasing prevalence in recent
decades. However, the immunological and cellular mechanisms involved in allergic …

Deficiency of INPP4A promotes M2 macrophage polarization in eosinophilic chronic rhinosinusitis with nasal polyps

Y Xu, X Tong, P Liu, J Huang, S Chen, D Liu, T Gu… - Inflammation …, 2024 - Springer
Objective The treatment of eosinophilic chronic rhinosinusitis with nasal polyps (E-
CRSwNP) remains a challenge due to its complex pathogenesis. Inositol polyphosphate-4 …

Serum exosome-derived miR-146a-3p promotes macrophage M2 polarization in allergic rhinitis by targeting VAV3 via PI3K/AKT/mTOR pathway

C Xia, K Zhu, Y Zhang, J Chen, C Yu, T Gao… - International …, 2023 - Elsevier
Background Our previous study showed that miR-146a-3p was elevated in serum exosomes
of allergic rhinitis (AR) patients, but the underlying mechanisms were unclarified. This study …