Stimuli responsive dynamic transformations in supramolecular gels

S Panja, DJ Adams - Chemical Society Reviews, 2021 - pubs.rsc.org
Supramolecular gels are formed by the self-assembly of small molecules under the
influence of various non-covalent interactions. As the interactions are individually weak and …

Synthetic cells: from simple bio‐inspired modules to sophisticated integrated systems

C Guindani, LC da Silva, S Cao, T Ivanov… - Angewandte …, 2022 - Wiley Online Library
Bottom‐up synthetic biology is the science of building systems that mimic the structure and
function of living cells from scratch. To do this, researchers combine tools from chemistry …

Compartmentalizing cell-free systems: toward creating life-like artificial cells and beyond

E Cho, Y Lu - ACS Synthetic Biology, 2020 - ACS Publications
Building an artificial cell is a research area that is rigorously studied in the field of synthetic
biology. It has brought about much attention with the aim of ultimately constructing a natural …

Polarity-sensitive and membrane-specific probe quantitatively monitoring ferroptosis through fluorescence lifetime imaging

S Wu, Y Yan, H Hou, Z Huang, D Li, X Zhang… - Analytical …, 2022 - ACS Publications
As a new form of regulated cell death, ferroptosis is closely related to various diseases. To
interpret this biological behavior and monitor related pathological processes, it is necessary …

Growth, replication and division enable evolution of coacervate protocells

AD Slootbeek, MHI van Haren, IBA Smokers… - Chemical …, 2022 - pubs.rsc.org
Living and proliferating cells undergo repeated cycles of growth, replication and division, all
orchestrated by complex molecular networks. How a minimal cell cycle emerged and helped …

Synthesis of lipid membranes for artificial cells

KA Podolsky, NK Devaraj - Nature Reviews Chemistry, 2021 - nature.com
A major goal of synthetic biology is to understand the transition between non-living matter
and life. The bottom-up development of an artificial cell would provide a minimal system with …

Membrane mimetic chemistry in artificial cells

JA Vance, NK Devaraj - Journal of the American Chemical Society, 2021 - ACS Publications
Lipid membranes in cells are fluid structures that undergo constant synthesis, remodeling,
fission, and fusion. The dynamic nature of lipid membranes enables their use as adaptive …

Synthetic cells in biomedical applications

W Sato, T Zajkowski, F Moser… - Wiley Interdisciplinary …, 2022 - Wiley Online Library
Synthetic cells are engineered vesicles that can mimic one or more salient features of life.
These features include directed localization, sense‐and‐respond behavior, gene …

From vesicles toward protocells and minimal cells

M Imai, Y Sakuma, M Kurisu, P Walde - Soft Matter, 2022 - pubs.rsc.org
In contrast to ordinary condensed matter systems,“living systems” are unique. They are
based on molecular compartments that reproduce themselves through (i) an uptake of …

Chromatophores efficiently promote light-driven ATP synthesis and DNA transcription inside hybrid multicompartment artificial cells

E Altamura, P Albanese, R Marotta… - Proceedings of the …, 2021 - National Acad Sciences
The construction of energetically autonomous artificial protocells is one of the most
ambitious goals in bottom-up synthetic biology. Here, we show an efficient manner to build …