Abstract Coronavirus disease 2019 (COVID-19), caused by the Severe Acute Respiratory
Syndrome Coronavirus 2 (SARS-CoV-2), has currently led to a global pandemic with …

Epoxyeicosatrienoic acids (EETs) are metabolites of arachidonic acid by cytochrome P450
(CYP) epoxygenases, which include four regioisomers: 5, 6-EET, 8, 9-EET, 11, 12-EET, and …

Background: Brown adipose tissue (BAT) is an important tissue for thermogenesis, making it
a potential target to decrease the risks of obesity, type 2 diabetes, and cardiovascular …

Chemotherapy, nerve injuries, or diseases like multiple sclerosis can cause
pathophysiological processes of persistent and neuropathic pain. Thereby, the activation …

Age-associated changes leading to a decline in cardiac structure and function contribute to
the increased susceptibility and incidence of cardiovascular diseases (CVD) in elderly …

Thermogenesis is an energy demanding process by which endotherms produce heat to
maintain their body temperature in response to cold exposure. Mitochondria in the brown …

Endotoxemia elicits a multiorgan inflammatory response that results in cardiac dysfunction
and often leads to death. Inflammation-induced metabolism of endogenous N-3 and N-6 …

The octadecanoids are a broad class of lipids consisting of the oxygenated products of 18-
carbon fatty acids. Originally referring to production of the phytohormone jasmonic acid, the …

The incidence of heart failure (HF) is generally preceded by cardiac hypertrophy (CH), which
is the enlargement of cardiac myocytes in response to stress. During CH, the metabolism of …

Abstract Severe Corona Virus Disease is characterized by angiocentric inflammation of
lungs and cytokine storm leading to potentially fatal multiple organ failure. Several studies …