Anxiety disorders are the most prevalent psychiatric disorders and a leading cause of
disability. While there continues to be expansive research in posttraumatic stress disorder …

Generalized anxiety disorder (GAD) is a prevalent and highly disabling mental health
condition; however, there is still much to learn with regard to pertinent biomarkers, as well as …

Anxiety and stress-related disorders, namely posttraumatic stress disorder (PTSD),
generalized anxiety disorder (GAD), obsessive–compulsive disorder (ODC), social and …

The N-methyl-d-aspartate (NMDA) glutamate receptor antagonist ketamine may have rapid,
albeit transient, antidepressant properties. This study in patients with treatment-resistant …

Monoaminergic-based drugs remain the primary focus of pharmaceutical industry drug
discovery efforts for mood disorders, despite serious limitations regarding their ability to …

Generalized anxiety disorder (GAD) is common in community and clinical settings. The
associated individual and societal burden is substantial, but many of those who could …

Brain imaging research in anxiety disorders has become increasingly important, especially
in the last decade, because of the opportunity to validate neurobiological hypotheses for …

The most prevalent mental disorders, anxiety and mood disorders, are associated with both
functional and morphological brain changes that commonly involve the 'fear …

In patients with Alzheimer's disease (AD) and in a triple transgenic (3xTg AD) mouse model
of AD low glucose metabolism in the brain precedes loss of memory and cognitive decline …

Drugs acting at metabotropic glutamate receptors (mGluRs) are among the most promising
agents under development for the treatment of psychiatric disorders. The research in this …