Muscle wasting occurs in a variety of conditions, including both genetic diseases, such as
muscular dystrophies, and acquired disorders, ranging from muscle disuse to cancer …

Chargé, Sophie BP, and Michael A. Rudnicki. Cellular and Molecular Regulation of Muscle
Regeneration. Physiol Rev 84: 209–238, 2004; 10.1152/physrev. 00019.2003.—Under …

The muscle satellite cell was first described and actually named on the basis of its anatomic
location under the basement membrane surrounding each myofiber. For many years …

Skeletal muscle formation and growth require the fusion of myoblasts to form multinucleated
myofibers or myotubes, but few molecules are known to regulate myoblast fusion in …

Genetic regulatory networks governing skeletal myogenesis in the body are well
understood, yet their hierarchical relationships in the head remain unresolved. We show that …

Skeletal muscle regeneration comprises several overlapping cellular processes, including
inflammation and myogenesis. Prostaglandins (PGs) may regulate muscle regeneration …

The degenerative and regenerative roles of tumor necrosis factor α (TNF‐α), a pro‐
inflammatory cytokine with pleiotropic functions, were investigated by using TNF receptor 1 …

Hepatocyte growth factor (HGF) is the only known growth factor that activates quiescent
satellite cells in skeletal muscle. We hypothesized that local delivery of HGF may enhance …

Adult skeletal muscle possesses a remarkable regenerative capacity, due to the presence of
satellite cells, adult muscle stem cells. We used fate-mapping techniques in avian and …

Traumatic injuries, tumor resections, and degenerative diseases can damage skeletal
muscle and lead to functional impairment and severe disability. Skeletal muscle …