Curcumin: A potent agent to reverse epithelial-to-mesenchymal transition
A Bahrami, M Majeed, A Sahebkar - Cellular Oncology, 2019 - Springer
Background Epithelial-to-mesenchymal transition (EMT) is involved in tumor progression,
invasion, migration and metastasis. EMT is a process by which polarized epithelial cells …
invasion, migration and metastasis. EMT is a process by which polarized epithelial cells …
The Anti-fibrosis drug Pirfenidone modifies the immunosuppressive tumor microenvironment and prevents the progression of renal cell carcinoma by inhibiting tumor …
Transforming growth factor-β (TGF-β) plays a critical role in regulating cell growth and
differentiation. Epithelial to mesenchymal transition (EMT) induced by TGF-β promotes …
differentiation. Epithelial to mesenchymal transition (EMT) induced by TGF-β promotes …
[HTML][HTML] HES1 promotes breast cancer stem cells by elevating Slug in triple-negative breast cancer
X Li, Y Li, X Du, X Wang, S Guan, Y Cao… - International journal of …, 2021 - ncbi.nlm.nih.gov
Triple-negative breast cancer (TNBC) is the most aggressive subtype of breast cancer.
TNBC is enriched with breast cancer stem cells (BCSCs), which are responsible for cancer …
TNBC is enriched with breast cancer stem cells (BCSCs), which are responsible for cancer …
In vivo imaging of TGFβ signalling components using positron emission tomography
L Rotteveel, AJ Poot, HJ Bogaard, P Ten Dijke… - Drug Discovery …, 2019 - Elsevier
Highlights•The transforming growth factor β (TGFβ) pathway is important in disease.•Imaging
the TGFβ pathway is vital for understanding its role in disease.•An overview of existing …
the TGFβ pathway is vital for understanding its role in disease.•An overview of existing …
Oncolytic adenovirus encoding LIGHT (TNFSF14) inhibits tumor growth via activating anti-tumor immune responses in 4T1 mouse mammary tumor model in immune …
S Dai, Y Lv, W Xu, Y Yang, C Liu, X Dong… - Cancer Gene …, 2020 - nature.com
LIGHT, also known as tumor-necrosis factor (TNF) superfamily member 14 (TNFSF14), is
predominantly expressed on activated immune cells and some tumor cells. LIGHT is a …
predominantly expressed on activated immune cells and some tumor cells. LIGHT is a …
[HTML][HTML] Ski mediates TGF-β1-induced fibrosarcoma cell proliferation and promotes tumor growth
P Li, QS Wang, Y Zhai, RP Xiong, X Chen, P Liu… - Journal of …, 2020 - ncbi.nlm.nih.gov
Background: TGF-β1 promotes cell proliferation in only some tumors and exerts bidirectional
regulatory effects on the proliferation of fibroblasts. This study intends to explore whether the …
regulatory effects on the proliferation of fibroblasts. This study intends to explore whether the …
Breast tumor tissue inflammation but not lobular involution is associated with survival among breast cancer patients in the Multiethnic Cohort
Background This study investigated the association of breast lobular involution status and
three inflammatory markers as predictors of survival among breast cancer patients in the …
three inflammatory markers as predictors of survival among breast cancer patients in the …
Identification of molecular subtypes and prognostic features of breast cancer based on TGF-β signaling-related genes
MH Wang, YH Gao, J Qu, W Zhang - 2023 - researchsquare.com
Purpose: The TGF-β signaling system is well understood to be involved in numerous cancer
progressions, including cell invasion, epithelial-mesenchymal transition, and …
progressions, including cell invasion, epithelial-mesenchymal transition, and …