Emerging rules for subunit-based, multiantigenic, multistage chemically synthesized vaccines
ME Patarroyo, MA Patarroyo - Accounts of chemical research, 2008 - ACS Publications
Seventeen million people die of transmittable diseases and 2/3 of the world's population
suffer them annually. Malaria, tuberculosis, AIDS, hepatitis, and reemerging and new …
suffer them annually. Malaria, tuberculosis, AIDS, hepatitis, and reemerging and new …
Structural and immunological principles leading to chemically synthesized, multiantigenic, multistage, minimal subunit-based vaccine development
Dedicated to the memory of Professors Henry G. Kunkel and Bruce Merrifield (Rockefeller
University, New York), who introduced us to the fascinating worlds of immunology and …
University, New York), who introduced us to the fascinating worlds of immunology and …
Developmental Biology of Sporozoite-Host Interactions in Plasmodium falciparum Malaria: Implications for Vaccine Design
JE Garcia, A Puentes, ME Patarroyo - Clinical microbiology …, 2006 - Am Soc Microbiol
The Plasmodium falciparum sporozoite infects different types of cells in a mosquito's salivary
glands and human epithelial and Kuppfer cells and hepatocytes. These become …
glands and human epithelial and Kuppfer cells and hepatocytes. These become …
Intimate Molecular Interactions of P. falciparum Merozoite Proteins Involved in Invasion of Red Blood Cells and Their Implications for Vaccine Design
LE Rodriguez, H Curtidor, M Urquiza… - Chemical …, 2008 - ACS Publications
Intimate Molecular Interactions of P. falciparum Merozoite Proteins Involved in Invasion of Red
Blood Cells and Their Implications for Vaccine Design | Chemical Reviews ACS ACS …
Blood Cells and Their Implications for Vaccine Design | Chemical Reviews ACS ACS …
Strategies for developing multi‐epitope, subunit‐based, chemically synthesized anti‐malarial vaccines
ME Patarroyo, G Cifuentes, A Bermudez… - Journal of cellular …, 2008 - Wiley Online Library
• Introduction• P. falciparum invasion of RBCs• Merozoite proteins involved in invading
erythrocytes• Erythrocyte proteins involved in merozoite invasion• The state of current …
erythrocytes• Erythrocyte proteins involved in merozoite invasion• The state of current …
Splenectomised and spleen intact Aotus monkeys' immune response to Plasmodium vivax MSP-1 protein fragments and their high activity binding peptides
AY Sierra, CA Barrero, R Rodriguez, Y Silva… - Vaccine, 2003 - Elsevier
Two E. coli expressed recombinant polypeptides (rPvMSP-114 and rPvMSP-120) contained
in the 33kDa fragment, located within Plasmodium vivax merozoite surface protein (PvMSP …
in the 33kDa fragment, located within Plasmodium vivax merozoite surface protein (PvMSP …
Identifying putative Mycobacterium tuberculosis Rv2004c protein sequences that bind specifically to U937 macrophages and A549 epithelial cells
M Forero, Á Puentes, J Cortés, F Castillo… - Protein …, 2005 - Wiley Online Library
Virulence and immunity are still poorly understood in Mycobacterium tuberculosis. The
H37Rv M. tuberculosis laboratory strain genome has been completely sequenced, and this …
H37Rv M. tuberculosis laboratory strain genome has been completely sequenced, and this …
[HTML][HTML] Immune protection-inducing protein structures (IMPIPS) against malaria: the weapons needed for beating Odysseus
The review covers the functional and structural approach followed by our group for more
than 34 years in the search for a methodology that allows the rational design of chemically …
than 34 years in the search for a methodology that allows the rational design of chemically …
Gauche+ side-chain orientation as a key factor in the search for an immunogenic peptide mixture leading to a complete fully protective vaccine
A Bermúdez, D Calderon, A Moreno-Vranich… - Vaccine, 2014 - Elsevier
Topological and stereo-electron characteristics are essential in major histocompability class
II–peptide–T–cell receptor (MHC–p–TCR) complex formation for inducing an appropriate …
II–peptide–T–cell receptor (MHC–p–TCR) complex formation for inducing an appropriate …
Recent advances in the development of a chemically synthesised anti-malarial vaccine
H Curtidor, ME Patarroyo… - Expert Opinion on …, 2015 - Taylor & Francis
Introduction: Obtaining an effective antimalarial vaccine has represented one of the biggest
public health challenges over the last 50 years. Despite efforts by many laboratories around …
public health challenges over the last 50 years. Despite efforts by many laboratories around …