Bone-tissue engineering is a therapeutic target in the field of dental implant and orthopedic
surgery. It is therefore essential to find a microenvironment that enhances the growth and …

Heterodimeric bone morphogenetic proteins (BMPs) consist of disulfide-linked dimeric
monomers derived from different BMP members. Owing to this specific constitution pattern …

Mesenchymal stem cells (MSCs) are currently the most established cells for skeletal tissue
engineering and regeneration; however, their availability and capability of self-renewal are …

Osteoporosis is a reduction in skeletal mass due to an imbalance between bone formation
and bone resorption. Many researchers have tried to develop adjuvants as specific …

Bone regeneration achieved using mesenchymal stem cells (MSCs) and nonviral gene
therapy holds great promise for patients with fractures seemingly unable to heal. Previously …

Background Osteoarthritis (OA) in the horse is an economic and welfare issue and there are
no current disease modifying drugs available. Stem cells have been suggested as a …

Combination of mesoporous silica materials and bioactive factors is a promising niche-
mimetic solution as a hybrid bone substitution for bone tissue engineering. In this work, we …

To investigate the effects of Genistein on the osteogenic related gene expression profiles
during osteoblastic differentiation of human bone marrow mesenchymal stem cell (hBMSC) …

Improving the osteogenic activity of BMP-2 in vivo has significant clinical application value.
In this research, we use a clinical gelatin sponge scaffold loaded with BMP-2 and …

OBJECTIVE: To evaluate healing of surgically created large osteochondral defects in a
weight-bearing femoral condyle in response to delayed percutaneous direct injection of …