1, 2-Amino alcohols and their heterocyclic derivatives as chiral auxiliaries in asymmetric synthesis

DJ Ager, I Prakash, DR Schaad - Chemical Reviews, 1996 - ACS Publications
R-amino acid reductions, allow entry to other classes of compounds that are also useful as
the source of chiral centers, as with R-amino aldehydes, that, in turn, can be used in a …

Catalytic oxidation of organic substrates by molecular oxygen and hydrogen peroxide by multistep electron transfer—a biomimetic approach

J Piera, JE Bäckvall - Angewandte Chemie International …, 2008 - Wiley Online Library
Oxidation reactions are of fundamental importance in nature, and are key transformations in
organic synthesis. The development of new processes that employ transition metals as …

Catalytic asymmetric dihydroxylation

HC Kolb, MS VanNieuwenhze, KB Sharpless - Chemical Reviews, 1994 - ACS Publications
During the last decade a number of powerful asymmetric reactions have emerged as a result
of the growing need to develop efficient and practical syntheses of biologically active …

Large-volume en-bloc staining for electron microscopy-based connectomics

Y Hua, P Laserstein, M Helmstaedter - Nature communications, 2015 - nature.com
Large-scale connectomics requires dense staining of neuronal tissue blocks for electron
microscopy (EM). Here we report a large-volume dense en-bloc EM staining protocol that …

Searching for new reactivity (Nobel lecture)

KB Sharpless - Angewandte Chemie International Edition, 2002 - Wiley Online Library
The processes for the selective oxidation of olefins have long been among the most useful
tools for day‐to‐day organic synthesis. Herein, the focus is on the asymmetric‐epoxidation …

Palladium-catalysed hydroxylation and alkoxylation

S Enthaler - Chemical Society Reviews, 2011 - pubs.rsc.org
The formation of oxygen–carbon bonds is one of the fundamental transformations in organic
synthesis. In this regard the application of palladium-based catalysts has been extensively …

Catalytic enantioselective functionalization of unactivated terminal alkenes

JR Coombs, JP Morken - Angewandte Chemie International …, 2016 - Wiley Online Library
Terminal alkenes are readily available functional groups which appear in α‐olefins
produced by the chemical industry, and they appear in the products of many contemporary …

Catalytic asymmetric aminohydroxylation (AA) of olefins

G Li, HT Chang, KB Sharpless - … Chemie International Edition …, 1996 - Wiley Online Library
The/&hydroxyamino group is frequently found in biologically active molecules. We report
here that this important unit can now be synthesized directly from olefins in enantiomerically …

Recoverable catalysts for asymmetric organic synthesis

QH Fan, YM Li, ASC Chan - Chemical Reviews, 2002 - ACS Publications
Homogeneous asymmetric catalysis is one of the most important developments in chemistry
in the past several decades. 1-4 Thousands of chiral ligands and their transition metal …

Ion exchange resins: catalyst recovery and recycle

P Barbaro, F Liguori - Chemical reviews, 2009 - ACS Publications
Chemical synthesis is greatly facilitated by catalysis and further on by catalyst recovery and
recycle. Catalyst reuse increases the overall productivity and cost effectiveness of chemical …