Signaling receptors for TGF-β family members
CH Heldin, A Moustakas - Cold Spring Harbor …, 2016 - cshperspectives.cshlp.org
Transforming growth factor β (TGF-β) family members signal via heterotetrameric complexes
of type I and type II dual specificity kinase receptors. The activation and stability of the …
of type I and type II dual specificity kinase receptors. The activation and stability of the …
[HTML][HTML] A systematic review of microRNA in glioblastoma multiforme: micro-modulators in the mesenchymal mode of migration and invasion
HG Møller, AP Rasmussen, HH Andersen… - Molecular …, 2013 - Springer
Glioblastoma multiforme (GBM) is an incurable form of brain cancer with a very poor
prognosis. Because of its highly invasive nature, it is impossible to remove all tumor cells …
prognosis. Because of its highly invasive nature, it is impossible to remove all tumor cells …
circRNA_010383 acts as a sponge for miR-135a, and its downregulated expression contributes to renal fibrosis in diabetic nephropathy
F Peng, W Gong, S Li, B Yin, C Zhao, W Liu, X Chen… - Diabetes, 2021 - Am Diabetes Assoc
Diabetic nephropathy (DN), a vascular complication of diabetes, is the leading cause of
death in patients with diabetes. The contribution of aberrantly expressed circular RNAs …
death in patients with diabetes. The contribution of aberrantly expressed circular RNAs …
[HTML][HTML] Effect of microRNA-135a on cell proliferation, migration, invasion, apoptosis and tumor angiogenesis through the IGF-1/PI3K/Akt signaling pathway in non …
Y Zhou, S Li, J Li, D Wang, Q Li - Cellular physiology and biochemistry, 2017 - karger.com
Objective: This study explored the ability of microRNA-135a (miR-135a) to influence cell
proliferation, migration, invasion, apoptosis and tumor angiogenesis through the IGF …
proliferation, migration, invasion, apoptosis and tumor angiogenesis through the IGF …
MiR-135a promotes renal fibrosis in diabetic nephropathy by regulating TRPC1
F He, F Peng, X Xia, C Zhao, Q Luo, W Guan, Z Li, X Yu… - Diabetologia, 2014 - Springer
Aims/hypothesis The contribution of aberrantly expressed microRNAs (miRNAs) to diabetic
nephropathy in vivo is poorly understood. Methods Integrated comparative miRNA array …
nephropathy in vivo is poorly understood. Methods Integrated comparative miRNA array …
Decreased miRNA-637 is an unfavorable prognosis marker and promotes glioma cell growth, migration and invasion via direct targeting Akt1
T Que, Y Song, Z Liu, S Zheng, H Long, Z Li, Y Liu… - Oncogene, 2015 - nature.com
Although increasing evidence indicated that the deregulation of microRNAs (miRNAs)
contributes to tumorigenesis and invasion, little is known about the role of miR-637 in human …
contributes to tumorigenesis and invasion, little is known about the role of miR-637 in human …
[HTML][HTML] Oncogenic microRNA-155 down-regulates tumor suppressor CDC73 and promotes oral squamous cell carcinoma cell proliferation: implications for cancer …
MI Rather, MN Nagashri, SS Swamy… - Journal of Biological …, 2013 - ASBMB
The CDC73 gene is mutationally inactivated in hereditary and sporadic parathyroid tumors.
It negatively regulates β-catenin, cyclin D1, and c-MYC. Down-regulation of CDC73 has …
It negatively regulates β-catenin, cyclin D1, and c-MYC. Down-regulation of CDC73 has …
[HTML][HTML] miRNA-135a promotes breast cancer cell migration and invasion by targeting HOXA10
Y Chen, J Zhang, H Wang, J Zhao, C Xu, Y Du, X Luo… - BMC cancer, 2012 - Springer
Background miRNAs are a group of small RNA molecules regulating target genes by
inducing mRNA degradation or translational repression. Aberrant expression of miRNAs …
inducing mRNA degradation or translational repression. Aberrant expression of miRNAs …
[HTML][HTML] MicroRNA delivery systems in glioma therapy and perspectives: A systematic review
JM Jiménez-Morales, YE Hernández-Cuenca… - Journal of Controlled …, 2022 - Elsevier
Gliomas are the deadliest of all primary brain tumors, and they constitute a serious global
health problem. MicroRNAs (miRNAs) are gene expression regulators associated with …
health problem. MicroRNAs (miRNAs) are gene expression regulators associated with …
[HTML][HTML] MiR-135a biogenesis and regulation in malignancy: a new hope for cancer research and therapy
Z Cao, J Qiu, G Yang, Y Liu, W Luo, L You… - Cancer biology & …, 2020 - ncbi.nlm.nih.gov
MicroRNAs (miRNAs) are evolutionarily conserved small non-coding RNAs that affect
posttranscriptional regulation by binding to the 3′-untranslated region of target messenger …
posttranscriptional regulation by binding to the 3′-untranslated region of target messenger …