Abstract Structure and function are highly correlated in the vertebrate retina, a sensory tissue
that is organized into cell layers with microcircuits working in parallel and together to encode …

Macular dystrophies (MDs) consist of a heterogeneous group of disorders that are
characterised by bilateral symmetrical central visual loss. Advances in genetic testing over …

PURPOSE: To establish a normative database of peripapillary retinal nerve fiber layer
(RNFL) thickness, macular thickness, and retinal layer thickness in healthy North American …

In the retina, like in most other brain regions, developing neurons are arranged into distinct
layers giving the mature tissue its stratified appearance. This process needs to be highly …

Adaptive optics (AO) ophthalmoscopy allows for non-invasive retinal phenotyping on a
microscopic scale, thereby helping to improve our understanding of retinal diseases. An …

Purpose.: To study the relationship between cone spacing and density and clinical
measures of visual function near the fovea. Methods.: High-resolution images of the …

The array of therapeutic options available to clinicians for treating retinal disease is
expanding. With these advances comes the need for better understanding of the etiology of …

Adaptive optics (AO) imaging enables direct, objective assessments of retinal cells.
Applications of AO show great promise in advancing our understanding of the etiology of …

X-linked Retinoschisis (XLRS) is an early-onset transretinal dystrophy, often with a
prominent macular component, that affects males and generally spares heterozygous …

Purpose. To develop and test the application of an adaptive optics scanning laser
ophthalmoscope (AOSLO) with eye tracking for high-resolution microperimetric testing …