Almost two decades of genetic research in Parkinson's disease (PD) have remarkably
increased our knowledge regarding the genetic basis of PD with numerous genes and …

Parkinson disease (PD) is a multifactorial neurodegenerative disease that was long
considered the result of environmental factors. In the past 15 years, however, a genetic …

Genome-wide association studies (GWAS) have identified numerous genetic variants
associated with complex diseases, but mechanistic insights are impeded by a lack of …

Parkinson disease is a complex, multifactorial neurodegenerative disease. Although a
heritable basis was originally thought unlikely, recent studies have implicated several genes …

Over the past few years, genetic findings have changed our views on the molecular
pathogenesis of Parkinson disease (PD), as mutations in a growing number of genes have …

Increased α-synuclein gene (SNCA) dosage due to locus multiplication causes autosomal
dominant Parkinson's disease (PD). Variation in SNCA expression may be critical in …

Parkinson's disease (PD) is the second most common age related neurodegenerative
disorder worldwide and presents as a progressive movement disorder. Globally seven …

Background A functional repeat polymorphism in theSNCApromoter (REP1) conveys
susceptibility for Parkinson disease (PD). There is also increasing evidence that single …

Over the last few years, several genes for monogenic forms of Parkinson's disease (PD)
have been mapped and/or cloned. Mutations have been identified in the gene for α …

Genetics of Parkinson's disease : Current Opinion in Neurology Genetics of Parkinson's
disease : Current Opinion in Neurology Log in or Register Subscribe to journalSubscribe Get …