[HTML][HTML] Experimental Protocols to Test Aortic Soft Tissues: A Systematic Review

R Valente, A Mourato, J Xavier, P Sousa, T Domingues… - Bioengineering, 2024 - mdpi.com
Experimental protocols are fundamental for quantifying the mechanical behaviour of soft
tissue. These data are crucial for advancing the understanding of soft tissue mechanics …

Full-field strain mapping of healthy and pathological mouse aortas using stereo digital image correlation

BA Lane, RJ Cardoza, SM Lessner… - Journal of the …, 2023 - Elsevier
The murine aorta is a complex, heterogeneous structure that undergoes large and
sometimes asymmetrical deformations under loading. For analytical convenience …

Resorbable vascular grafts show rapid cellularization and degradation in the ovine carotid

CET Stowell, X Li, MH Matsunaga… - Journal of tissue …, 2020 - Wiley Online Library
Small‐diameter vascular grafts perform poorly as arterial bypasses. We developed a cell‐
free, resorbable graft intended to remodel in situ into a living vessel. The graft consisted of a …

Hybrid fibroin/polyurethane small-diameter vascular grafts: from fabrication to in vivo preliminary assessment

A Caldiroli, E Pederzani, M Pezzotta… - Biomedical …, 2022 - iopscience.iop.org
To address the need of alternatives to autologous vessels for small-calibre vascular
applications (eg cardiac surgery), a bio-hybrid semi-degradable material composed of silk …

Mapping the unicellular transcriptome of the ascending thoracic aorta to changes in mechanosensing and mechanoadaptation during aging

CF Rivera, YM Farra, M Silvestro, S Medvedovsky… - Aging …, 2024 - Wiley Online Library
Aortic stiffening is an inevitable manifestation of chronological aging, yet the mechano‐
molecular programs that orchestrate region‐and layer‐specific adaptations along the length …

Novel payloads to mitigate maladaptive inward arterial remodeling in drug-coated balloon therapy

T Shazly, M Uline, C Webb… - Journal of …, 2023 - asmedigitalcollection.asme.org
Drug-coated balloon therapy is a minimally-invasive endovascular approach to treat
obstructive arterial disease, with increasing utilization in the peripheral circulation due to …

Absence of LTBP-3 attenuates the aneurysmal phenotype but not spinal effects on the aorta in Marfan syndrome

A Korneva, L Zilberberg, DB Rifkin… - … and modeling in …, 2019 - Springer
Fibrillin-1 is an elastin-associated glycoprotein that contributes to the long-term fatigue
resistance of elastic fibers as well as to the bioavailability of transforming growth factor-beta …

Hydrophilic Coating Microstructure Mediates Acute Drug Transfer in Drug-Coated Balloon Therapy

T Shazly, JF Eberth, CJ Kostelnik, MJ Uline… - ACS Applied Bio …, 2024 - ACS Publications
Drug-coated balloon (DCB) therapy is a promising endovascular treatment for obstructive
arterial disease. The goal of DCB therapy is restoration of lumen patency in a stenotic …

Are ovine and porcine carotid arteries equivalent animal models for experimental cardiac surgery: a quantitative histological comparison

M Grajciarová, D Turek, A Malečková, R Pálek… - Annals of Anatomy …, 2022 - Elsevier
Background Coronary artery bypass grafting (CABG) is a common cardiac surgery.
Manufacturing small-diameter (2–5 mm) vascular grafts for CABG is important for patients …

Targeted gold nanoparticles as an indicator of mechanical damage in an elastase model of aortic aneurysm

BA Lane, X Wang, SM Lessner, NR Vyavahare… - Annals of biomedical …, 2020 - Springer
Elastin is a key structural protein and its pathological degradation deterministic in aortic
aneurysm (AA) outcomes. Unfortunately, using current diagnostic and clinical surveillance …