Methicillin-resistant Staphylococcus aureus (MRSA) is one of the most successful modern
pathogens. The same organism that lives as a commensal and is transmitted in both health …

The current duration of therapy in patients with Staphylococcus aureus bacteremia (SAB) is
based on differentiating complicated from uncomplicated disease. While this approach …

Bloodstream infections (BSIs) are common in hospitals, often life-threatening and increasing
in prevalence. Microorganisms in the blood are usually rapidly cleared by the immune …

Background Staphylococcus aureus bloodstream infection is treated with at least 14 days of
intravenous antimicrobials. We assessed the efficacy and safety of an early switch to oral …

Background Microbial cell-free DNA (mcfDNA) sequencing of plasma can identify the
presence of a pathogen in a host. In this study, we evaluated the duration of pathogen …

Abstract Background Bloodstream infections (BSIs) with methicillin-susceptible
Staphylococcus aureus (MSSA) are associated with significant morbidity and mortality. Our …

Non-adherence in non-inferiority trials can affect treatment effect estimates and often
increases the chance of claiming non-inferiority under the standard intention-to-treat …

Sepsis mortality has improved following advancements in early recognition and
standardized management, including emphasis on early administration of appropriate …

Staphylococcus aureus of the many staphylococcal species is the most common cause of
both skin and soft tissue infection and severe staphylococcal infections including …

Background Telemedicine use is increasing in many specialties, but its impact on clinical
outcomes in infectious diseases has not been systematically reviewed. We reviewed the …