OCEAN: a randomized Phase III study of melflufen+ dexamethasone to treat relapsed refractory multiple myeloma

F Schjesvold, P Robak, L Pour, J Aschan… - Future …, 2020 - Taylor & Francis
Melflufen is a novel peptide–drug conjugate that rapidly delivers a cytotoxic payload into
tumor cells. It has emerged as a potential new multiple myeloma treatment, particularly for …

Monoclonal gammopathies of renal significance: Renal biopsy and beyond

P Menè, L De Alexandris, A Moioli, S Raffa… - Cancers, 2020 - mdpi.com
Monoclonal Gammopathies of Renal Significance (MGRS) are a rather heterogeneous
group of renal disorders caused by a circulating monoclonal (MC) immunoglobulin (Ig) …

Clinical features and survival outcomes in IgD myeloma: a study by Asia Myeloma Network (AMN)

J Liu, X Hu, Y Jia, J Lu, JH Lee, K Kim, W Chen, A Liu… - Leukemia, 2021 - nature.com
Given the lack of large cohort with comprehensive clinical and cytogenetic assessment,
knowledge about IgD myeloma is obtained mostly from a limited sample size [7]. Therefore …

Renal insufficiency predicts worse prognosis in newly diagnosed IgD multiple myeloma patients

G Yan, H Li, Y Zhang, C Xia, M Wang, Y Jia… - Frontiers in …, 2022 - frontiersin.org
Objective IgD multiple myeloma (MM) is a rare type of MM, accounting for about 1%–2% of
all MMs. IgD MM always causes kidney damage and even leads to renal failure, which is the …

[HTML][HTML] Efficacy and safety of chimeric antigen receptor T-cell therapy for relapsed/refractory immunoglobulin D multiple myeloma

W Chen, Y Wang, K Qi, M Shi, J Cao, R Bhansali… - … and Cellular Therapy, 2021 - Elsevier
Immunoglobulin D (IgD) multiple myeloma (MM) is a rare subtype of MM that carries a worse
prognosis than non-IgD subtypes. Compared with non-IgD subtypes, IgD MM is associated …

[HTML][HTML] Characteristics of 15 Subjects Affected by IgD Multiple Myeloma and the Key Role of the Laboratory in Diagnosis: A Retrospective Study Report and Literature …

J Intra, S Pezzatti, R Brivio, M Carpenedo… - International Journal of …, 2024 - mdpi.com
Immunoglobulin D (IgD) myeloma represents an uncommon subtype of multiple myeloma
(MM), accounting for 1–2% of cases. Subjects affected by IgD MM have been demonstrated …

IgD multiple myeloma: biology, diagnosis, and treatment

PA Egan, SJM O'Connor, WI Deighan… - Leukemia & …, 2022 - Taylor & Francis
IgD multiple myeloma is uncommon. Patients generally present at a younger age and have
shorter progression free and overall survivals (OSs). Its rarity has inhibited development of a …

Case Report: A case of IgD lambda/lambda Multiple Myeloma in patient with acute renal failure and without monoclonal spike in serum electrophoresis

T Troiano, V Brescia, L De Marinis… - Frontiers in …, 2022 - frontiersin.org
Background IgD Multiple Myeloma is a rare form of plasma cell dyscrasia and accounts for
approximately 1-2% of all cases of Multiple Myeloma. It mainly affects young, male subjects; …

IgD subtype but not IgM or non-secretory is a prognostic marker for poor survival following autologous hematopoietic cell transplantation in multiple myeloma. Results …

S Lawless, G Sbianchi, C Morris, S Iacobelli… - … Myeloma and Leukemia, 2021 - Elsevier
Abstract Background The Collaboration to Collect Autologous Transplant Outcomes in
Lymphoma and Myeloma (CALM) study has provided an opportunity to evaluate the real …

Clinical characteristics and survival of patients with IgD multiple myeloma

Y Li, Z Cai - Blood Science, 2021 - mednexus.org
MM (multiple myeloma) accounts for about 10% of hematological malignancies and 1% of
cancer. IgD myeloma is a rare type of MM. It was reported that IgD type accounts for about …