Vitamin D deficiency is the most common nutritional deficiency, affecting almost one billion
people worldwide. Vitamin D is mostly known for its role in intestinal calcium absorption and …

1, 25-Dihydroxvitamin D3 [1, 25 (OH) 2D3] is the hormonally active form of vitamin D. The
genomic mechanism of 1, 25 (OH) 2D3 action involves the direct binding of the 1, 25 (OH) …

The endothelium can evoke relaxations of the underlying vascular smooth muscle, by
releasing vasodilator substances. The best‐characterized endothelium‐derived relaxing …

Vitamin D plays a classical hormonal role in skeletal health by regulating calcium and
phosphorus metabolism. Vitamin D metabolites also have physiological functions in …

Vitamin D, a fat-soluble prohormone, has wide-ranging roles in the regulation of many
physiological processes through their interactions with the vitamin D receptors (VDR). It …

We recognize that increased systolic pressure is the most challenging form of hypertension
today and that pulse pressure as an independent cardiovascular risk factor has focused …

The aim of this study is to determine and critically evaluate the plausible relationships of
vitamin D with extra-skeletal tissues in humans. Severe vitamin D deficiency results in rickets …

The vitamin D hormone 1α, 25-dihydroxyvitamin D3 [1, 25 (OH) 2D3] is essential for the
preservation of serum calcium and phosphate levels but may also be important for the …

Vitamin D, besides having an essential role in calcium and bone metabolism, also acts as a
mediator of many non-calcemic effects through modulations of several biological responses …

The systemic autoimmune disease rheumatoid arthritis (RA) is characterized by increased
cardiovascular mortality and morbidity and is an independent cardiovascular risk factor …