Mediterranean products as promising source of multi-target agents in the treatment of metabolic syndrome

D Bagetta, A Maruca, A Lupia, F Mesiti… - European Journal of …, 2020 - Elsevier
Alteration of nutritional habits play an essential role on the risk of developing Metabolic
Syndrome (MetS). Several epidemiological studies have shown that assuming diets rich of …

An Insight of Plant Source, Toxicological Profile, and Pharmacological Activities of Iridoid Loganic Acid: A ComprehensiveReview

A Aktar, S Bhuia, R Chowdhury, J Ferdous… - Chemistry & …, 2024 - Wiley Online Library
This study evaluates the pharmacological effects of iridoid glucoside loganic acid, a plant
constituent with diverse properties, based on literature, and explores the underlying cellular …

Phyto-metabolomics of phlogacanthus thyrsiformis by using LC-ESI-QTOF-MS/MS and GC/QTOF-MS: Evaluation of antioxidant and enzyme inhibition potential of …

S Ponneganti, US Murty, C Bagul, RM Borkar… - Food Research …, 2022 - Elsevier
Phlogacanthus thyrsiformis (P. thyrsiformis) is a non-conventional edible plant that has been
used as a vegetable and as a traditional medicine to treat various diseases. This non …

Isolation, semi-synthesis, docking-based prediction, and bioassay-based activity of Dolichandrone spathacea iridoids: new catalpol derivatives as glucosidase …

TTP Thao, TQ Bui, PT Quy, NC Bao, T Van Loc… - RSC …, 2021 - pubs.rsc.org
Dolichandrone spathacea iridoids are promising anti-diabetic inhibitors towards α-
glucosidase protein (PDB-3W37) and oligo-1, 6-glucosidase protein (PDB-3AJ7). Five …

Insights into brain glycogen metabolism: the structure of human brain glycogen phosphorylase

C Mathieu, IL de La Sierra-Gallay, R Duval, X Xu… - Journal of Biological …, 2016 - ASBMB
Brain glycogen metabolism plays a critical role in major brain functions such as learning or
memory consolidation. However, alteration of glycogen metabolism and glycogen …

Promising antidiabetic drugs, medicinal plants and herbs: An update

MI Yatoo, A Saxena, A Gopalakris… - International Journal of …, 2017 - elibrary.ru
Diabetes is a chronic endocrine disease with global prevalence and rising incidence.
Diabetes represents a major health issue in all age groups in the present times owing to its …

Fenugreek (Trigonella foenum-graecum L.) seed: promising source of nutraceutical

UM Srinivasa, MM Naidu - Studies in Natural Products Chemistry, 2021 - Elsevier
Fenugreek (Trigonella foenum-graecum L.) seeds are used widely in culinary preparations
and in traditional medicine. The biomedical activities of fenugreek are generally attributed to …

A systematic review of the protective role of swertiamarin in cardiac and metabolic diseases

XY Leong, PV Thanikachalam, M Pandey… - Biomedicine & …, 2016 - Elsevier
Background Swertiamarin, is a secoiridoid glycoside found in genera of Enicostemma
Species (Enicostemma littorale and Enicostemma axillare) belonging to the family of …

Anti-diabetic effects of natural products an overview of therapeutic strategies

J Park, HJ Jang - Molecular & cellular toxicology, 2017 - Springer
Diabetes mellitus, a large part of metabolic disorder, is characterized by persistent
hyperglycemia. The number of people suffering from diabetes is rapidly increasing …

Biologically active secoiridoids: A comprehensive update

Z Peng, J He, Y Cheng, J Xu… - Medicinal Research …, 2023 - Wiley Online Library
Secoiridoids are natural products of cyclopentane monoterpene derivatives that are formed
by splitting the rings of cyclomethene oxime compounds at C‐7 and C‐8, and only account …