Somatic cell nuclear transfer (SCNT) has been an area of interest in the field of stem cell
research and regenerative medicine for the past 20 years. The main biological goal of SCNT …

The few viable clones obtained at the end of a typical cloning experiment are genetic copies
of the donor cell genome of a non-reproductive (somatic) or embryonic cell used for nuclear …

Somatic cell clones often fail at a developmental stage coincident with commencement of
differentiation. The transcription factor Oct4 is expressed during cleavage stages and is …

NUCLEAR TRANSFER is a procedure by which genetically identical individuals can be
created. The applications of these techniques for nuclear transfer will be in agricultural …

Cloning by nuclear transfer (NT) has been riddled with difficulties: most clones die before
birth and survivors frequently display growth abnormalities. The cross‐species similarity in …

Fetal‐derived fibroblast cells were transduced with replication defective vectors containing
the enhanced green fluorescent protein (EGFP). The transgenic cells were treated with …

We examined the in vitro developmental potential of nonactivated and activated enucleated
ova receiving cumulus cells at various stages of the cell cycle. Eleven to 29% of activated …

Somatic cell nuclear transfer embryos exhibit extensive epigenetic abnormalities, including
aberrant methylation and abnormal imprinted gene expression. In this study, a thorough …

It is remarkable that mammalian somatic cell nuclei can form whole individuals if they are
transferred to enucleated oocytes. Advancements in nuclear transfer technology can now be …

Somatic cell nuclear transfer (NT) offers new and exciting opportunities in many areas of
research and biotechnology. However, the field as a whole is still in its infancy, with …