Alzheimer's disease (AD) is the most common age-related neurodegenerative disorder that
is characterized by amyloid β-protein deposition in senile plaques, neurofibrillary tangles …

Alzheimer's disease (AD) is a frequent and disabling neurodegenerative disorder, in which
astrocytes participate in several pathophysiological processes including neuroinflammation …

Chronic exposure to uncontrollable stress causes loss of spines and dendrites in the
prefrontal cortex (PFC), a recently evolved brain region that provides top-down regulation of …

A number of chronic metabolic pathologies, including obesity, diabetes, cardiovascular
disease, asthma, and cancer, cluster together to present the greatest threat to human health …

Mushroom dendritic spine structures are essential for memory storage, and the loss of
mushroom spines may explain memory defects in Alzheimer's disease (AD). Here we show …

Neurodegenerative disorders, such as Alzheimer's disease (AD), Parkinson's disease (PD),
amyotrophic lateral sclerosis (ALS), Huntington's disease (HD) and spinocerebellar ataxias …

Little is known about age‐dependent changes in structure and function of astrocytes and of
the impact of these on the cognitive decline in the senescent brain. The prevalent view on …

Iron, through its participation in oxidation/reduction processes, is essential for the
physiological function of biological systems. In the brain, iron is involved in the development …

Alzheimer disease (AD) is the most common neurodegenerative disorder worldwide and is
at present, incurable. The accumulation of toxic amyloid-beta (Aβ) peptide aggregates in AD …

Ageing can occur at different rates, but what controls this variable rate is unknown. Here I
have developed a hypothesis that vitamin D may act to control the rate of ageing. The basis …