Recent progressions in biomedical and pharmaceutical applications of chitosan nanoparticles: A comprehensive review

EM Khalaf, NA Abood, RZ Atta… - International Journal of …, 2023 - Elsevier
Nowadays, the most common approaches in the prognosis, diagnosis, and treatment of
diseases are along with undeniable limitations. Thus, the ever-increasing need for using …

Chitin and chitosan derivatives as biomaterial resources for biological and biomedical applications

S Satitsri, C Muanprasat - Molecules, 2020 - mdpi.com
Chitin is a long-chain polymer of N-acetyl-glucosamine, which is regularly found in the
exoskeleton of arthropods including insects, shellfish and the cell wall of fungi. It has been …

Emerging and future strategies in the management of recalcitrant Candida auris

N Bandara, L Samaranayake - Medical Mycology, 2022 - academic.oup.com
Candida auris is an emerging, multi drug resistant fungal pathogen that has caused
infectious outbreaks in over 45 countries since its first isolation over a decade ago, leading …

Promising Drug Candidates and New Strategies for Fighting against the Emerging Superbug Candida auris

M Billamboz, Z Fatima, S Hameed, S Jawhara - Microorganisms, 2021 - mdpi.com
Invasive fungal infections represent an expanding threat to public health. During the past
decade, a paradigm shift of candidiasis from Candida albicans to non-albicans Candida …

Virulence of Candida auris from different clinical origins in Caenorhabditis elegans and Galleria mellonella host models

A Hernando-Ortiz, E Mateo, A Perez-Rodriguez… - Virulence, 2021 - Taylor & Francis
Candida auris is an emerging multidrug-resistant fungal pathogen responsible for
nosocomial outbreaks of invasive candidiasis. Although several studies on the pathogenicity …

Chitosan and chitooligosaccharides: antifungal potential and structural insights

MIG de Azevedo, PFN Souza… - Chemistry & …, 2024 - Wiley Online Library
Chitosan is a cationic polysaccharide derived from chitin deacetylation. This polysaccharide
and its oligosaccharides have many biological activities and can be used in several fields …

Galleria mellonella for systemic assessment of anti-Candida auris using amphotericin B loaded in nanoemulsion

GD Marena, MADS Ramos, LC Lima, M Chorilli… - Science of The Total …, 2022 - Elsevier
Galleria mellonella is a model that uses adult larvae to assess the prophylactic, therapeutic,
and acute toxic potential of substances. Given their benefits, G. mellonella models are being …

The Galleria mellonella infection model as a system to investigate the virulence of Candida auris strains

D Romera, JJ Aguilera-Correa… - Pathogens and …, 2020 - academic.oup.com
Candida auris is a multiresistant pathogenic yeast commonly isolated from bloodstream
infections in immunocompromised patients. In this work, we infected Galleria mellonella …

Benzamidine Conjugation Converts Expelled Potential Active Agents into Antifungals against Drug-Resistant Fungi

X Wang, X Jin, Z Xie, H Zhang, T Liu… - Journal of Medicinal …, 2023 - ACS Publications
Fungal infections present a growing global public health concern, necessitating the
development of novel antifungal drugs. However, many potential antifungals, particularly the …

Chitosan-based sponges containing clotrimazole for the topical management of vulvovaginal candidiasis

F Martins, DL Morgado, B Sarmento… - International Journal of …, 2023 - Elsevier
Vulvovaginal candidiasis (VVC) persists as a worrying women's healthcare issue, often
relying on suboptimal therapeutics. Novel intravaginal dosage forms focusing on improving …