Intermediate filaments (IFs) are composed of one or more members of a large family of
cytoskeletal proteins, whose expression is cell-and tissue type-specific. Their importance in …

The cells and tissues that make up our body manage contradictory mechanical demands. It
is crucial for their survival to be able to withstand large mechanical loads, but it is equally …

The biological effects of circularly polarized light on living cells are considered to be
negligibly weak. Here, we show that the differentiation of neural stem cells into neurons can …

Collective cell migration requires maintenance of adhesive contacts between adjacent cells,
coordination of polarized cell protrusions, and generation of propulsive traction forces. We …

Desmin is the primary intermediate filament (IF) of cardiac, skeletal, and smooth muscle. By
linking the contractile myofibrils to the sarcolemma and cellular organelles, desmin IF …

Fibrin is a protein polymer that forms the viscoelastic scaffold of blood clots and thrombi.
Despite the critical importance of fibrin deformability for outcomes of bleeding and …

Intermediate filaments (IFs) are major constituents of the cytoskeleton and nuclear boundary
in animal cells. They are of prime importance for the functional organization of structural …

Nuclear lamins are type V intermediate filament proteins that polymerize into complex
filamentous meshworks at the nuclear periphery and in less structured forms throughout the …

Vimentin intermediate filaments (VIF) extend throughout the rear and perinuclear regions of
migrating fibroblasts, but only nonfilamentous vimentin particles are present in lamellipodial …

The intermediate filament protein desmin is an essential component of the extra-sarcomeric
cytoskeleton in muscle cells. This three-dimensional filamentous framework exerts central …