Hypertension: do inflammation and immunity hold the key to solving this epidemic?

MS Madhur, F Elijovich, MR Alexander, A Pitzer… - Circulation …, 2021 - Am Heart Assoc
Elevated cardiovascular risk including stroke, heart failure, and heart attack is present even
after normalization of blood pressure in patients with hypertension. Underlying immune cell …

Hypertension and COVID-19: current evidence and perspectives

G Gallo, V Calvez, C Savoia - High Blood Pressure & Cardiovascular …, 2022 - Springer
Abstract Coronavirus disease 2019 (COVID-19) outbreak, caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2), represents a real challenge for health …

Hypertension, a moving target in COVID-19: current views and perspectives

C Savoia, M Volpe, R Kreutz - Circulation Research, 2021 - Am Heart Assoc
Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) associates with a considerable high rate of mortality and …

Inflammation and hypertension: Underlying mechanisms and emerging understandings

D Aboukhater, B Morad, N Nasrallah… - Journal of cellular …, 2023 - Wiley Online Library
Hypertension remains a major contributor to cardiovascular disease (CVD), a leading cause
of global death. One of the major insults that drive increased blood pressure is inflammation …

Cardiovascular disease risk in rheumatoid arthritis anno 2022

B Dijkshoorn, R Raadsen, MT Nurmohamed - Journal of clinical medicine, 2022 - mdpi.com
The risk for developing cardiovascular diseases (CVD) in rheumatoid arthritis (RA) patients
is 1.5 times higher compared to the general population. This risk is partly due to the …

Salt sensitivity of blood pressure in women

CT Barris, JL Faulkner, EJ Belin de Chantemèle - Hypertension, 2023 - Am Heart Assoc
Several clinical and large population studies indicate that women are more salt-sensitive
than men, yet the precise mechanisms by which the sexually dimorphic onset manifests …

Targeting inflammation: a potential approach for the treatment of depression

S Bhatt, T Devadoss, NK Jha, M Baidya, G Gupta… - Metabolic Brain …, 2023 - Springer
Major depressive disorder (MDD) or Depression is one of the serious neuropsychiatric
disorders affecting over 280 million people worldwide. It is 4th important cause of disability …

Pathophysiology and genetics of salt-sensitive hypertension

D Maaliki, MM Itani, HA Itani - Frontiers in Physiology, 2022 - frontiersin.org
Most hypertensive cases are primary and heavily associated with modifiable risk factors like
salt intake. Evidence suggests that even small reductions in salt consumption reduce blood …

Nanocurcumin combined with insulin alleviates diabetic kidney disease through P38/P53 signaling axis

R Ganugula, NK Nuthalapati, S Dwivedi, D Zou… - Journal of Controlled …, 2023 - Elsevier
Treatments for diabetic kidney disease (DKD) mainly focus on managing hyperglycemia and
hypertension, but emerging evidence suggests that inflammation also plays a role in the …

Eicosanoid-regulated myeloid ENaC and isolevuglandin formation in human salt-sensitive hypertension

LA Ertuglu, A Pitzer Mutchler, S Jamison, CL Laffer… - …, 2024 - Am Heart Assoc
BACKGROUND: The mechanisms by which salt increases blood pressure in people with
salt sensitivity remain unclear. Our previous studies found that high sodium enters antigen …