FTO and obesity: mechanisms of association
X Zhao, Y Yang, BF Sun, YL Zhao, YG Yang - Current diabetes reports, 2014 - Springer
The Fat mass and obesity associated (FTO) gene is a newly identified genetic factor for
obesity. However, the exact molecular mechanisms responsible for the effect of FTO on …
obesity. However, the exact molecular mechanisms responsible for the effect of FTO on …
N6-methyladenosine-dependent signalling in cancer progression and insights into cancer therapies
F Tan, M Zhao, F Xiong, Y Wang, S Zhang… - Journal of Experimental …, 2021 - Springer
Abstract The N6-methyladenosine (m6A) modification is a dynamic and reversible
epigenetic modification, which is co-transcriptionally deposited by a methyltransferase …
epigenetic modification, which is co-transcriptionally deposited by a methyltransferase …
Sex modifies the association between the CLOCK variant rs1801260 and BMI in school-age children
Y Meng, B Lohse, L Cunningham-Sabo - PLoS One, 2020 - journals.plos.org
Disruption of circadian rhythms and variations in the FTO gene may interfere with energy
homeostasis and play a role in the development of obesity. The current study assessed the …
homeostasis and play a role in the development of obesity. The current study assessed the …
The emerging roles of N6-methyladenosine RNA modifications in thyroid cancer
X Xu, J Zhao, M Yang, L Han, X Yuan, W Chi… - European Journal of …, 2023 - Springer
Thyroid cancer (TC) is the most predominant malignancy of the endocrine system, with
steadily growing occurrence and morbidity worldwide. Although diagnostic and therapeutic …
steadily growing occurrence and morbidity worldwide. Although diagnostic and therapeutic …
Ionizing radiation and chemical oxidant exposure impacts on Cryptococcus neoformans transfer RNAs
M Kelley, MJ Paulines, G Yoshida, R Myers, M Jora… - PloS one, 2022 - journals.plos.org
Cryptococcus neoformans is a fungus that is able to survive abnormally high levels of
ionizing radiation (IR). The radiolysis of water by IR generates reactive oxygen species …
ionizing radiation (IR). The radiolysis of water by IR generates reactive oxygen species …
[HTML][HTML] Cell Differentiation and Aging Lead To Up-Regulation of FTO, While the ALKBH5 Protein Level Was Stable During Aging but Up-Regulated During in vitro …
J Krejčí, OA Arcidiacono, R Čegan… - Physiological …, 2023 - ncbi.nlm.nih.gov
FTO and ALKBH5 proteins are essential erasers of N 6-adenosine methylation in RNA. We
studied how levels of FTO and ALKBH5 proteins changed during mouse embryonic …
studied how levels of FTO and ALKBH5 proteins changed during mouse embryonic …
A primer for junior trainees: Recognition of RNA modifications by RNA‐binding proteins
M Angelo, Y Bhargava, ST Aoki - Biochemistry and Molecular …, 2024 - Wiley Online Library
The complexity of RNA cannot be fully expressed with the canonical A, C, G, and U
alphabet. To date, over 170 distinct chemical modifications to RNA have been discovered in …
alphabet. To date, over 170 distinct chemical modifications to RNA have been discovered in …