Endothelial dysfunction in COVID-19: an overview of evidence, biomarkers, mechanisms and potential therapies
The fight against coronavirus disease 2019 (COVID-19) caused by SARS-CoV-2 infection is
still raging. However, the pathophysiology of acute and post-acute manifestations of COVID …
still raging. However, the pathophysiology of acute and post-acute manifestations of COVID …
Adverse effects of COVID-19 mRNA vaccines: the spike hypothesis
Vaccination is a major tool for mitigating the coronavirus disease 2019 (COVID-19)
pandemic, and mRNA vaccines are central to the ongoing vaccination campaign that is …
pandemic, and mRNA vaccines are central to the ongoing vaccination campaign that is …
Persistent circulating severe acute respiratory syndrome coronavirus 2 spike is associated with post-acute coronavirus disease 2019 sequelae
The diagnosis of postacute sequelae of coronavirus disease 2019 (PASC) poses an
ongoing medical challenge. To identify biomarkers associated with PASC we analyzed …
ongoing medical challenge. To identify biomarkers associated with PASC we analyzed …
Circulating spike protein detected in post–COVID-19 mRNA vaccine myocarditis
Background: Cases of adolescents and young adults developing myocarditis after
vaccination with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)–targeted …
vaccination with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)–targeted …
[HTML][HTML] Serious adverse events of special interest following mRNA COVID-19 vaccination in randomized trials in adults
J Fraiman, J Erviti, M Jones, S Greenland, P Whelan… - Vaccine, 2022 - Elsevier
Introduction In 2020, prior to COVID-19 vaccine rollout, the Brighton Collaboration created a
priority list, endorsed by the World Health Organization, of potential adverse events relevant …
priority list, endorsed by the World Health Organization, of potential adverse events relevant …
[HTML][HTML] Metformin: Is it a drug for all reasons and diseases?
CR Triggle, I Mohammed, K Bshesh, I Marei, K Ye… - Metabolism, 2022 - Elsevier
Metformin was first used to treat type 2 diabetes in the late 1950s and in 2022 remains the
first-choice drug used daily by approximately 150 million people. An accumulation of …
first-choice drug used daily by approximately 150 million people. An accumulation of …
The disease severity and clinical outcomes of the SARS-CoV-2 variants of concern
With the continuation of the pandemic, many severe acute respiratory syndrome coronavirus
2 (SARS-CoV-2) variants have appeared around the world. Owing to a possible risk of …
2 (SARS-CoV-2) variants have appeared around the world. Owing to a possible risk of …
Host genetic factors determining COVID-19 susceptibility and severity
TP Velavan, SR Pallerla, J Rüter, Y Augustin… - …, 2021 - thelancet.com
The COVID-19 pandemic caused by the Severe Acute Respiratory Syndrome Coronavirus-2
(SARS-CoV-2) poses an unprecedented challenge to humanity. SARS-CoV-2 infections …
(SARS-CoV-2) poses an unprecedented challenge to humanity. SARS-CoV-2 infections …
Could SARS-CoV-2 spike protein be responsible for long-COVID syndrome?
TC Theoharides - Molecular Neurobiology, 2022 - Springer
SARS-CoV-2 infects cells via its spike protein binding to its surface receptor on target cells
and results in acute symptoms involving especially the lungs known as COVID-19. However …
and results in acute symptoms involving especially the lungs known as COVID-19. However …
[HTML][HTML] Angiotensin-converting enzyme 2—at the heart of the COVID-19 pandemic
ACE2 is the indispensable entry receptor for SARS-CoV and SARS-CoV-2. Because of the
COVID-19 pandemic, it has become one of the most therapeutically targeted human …
COVID-19 pandemic, it has become one of the most therapeutically targeted human …