Sepsis, a dysregulated host response to infection characterized by organ failure, is one of
the leading causes of death worldwide. Disbalances of the immune response play an …

Dear Editor, We read the article by Wu et al. published on Critical Care with great interest [1].
In light of the recent disclosure of clinical trials regarding the use of corticosteroids in the …

Background The role of corticosteroids in the treatment of community-acquired pneumonia
(CAP) remains uncertain. We conducted an updated meta-analysis to investigate the …

Acute cognitive impairments termed delirium often occur after inflammatory insults in elderly
patients. While previous preclinical studies suggest mitochondria as a target for reducing …

Introduction Community-acquired pneumonia (CAP) is a common infection associated with
high morbimortality and a highly deleterious impact on patients' quality of life and …

Effects of corticosteroids on severe community-acquired pneumonia: a closer look at the
evidence | Critical Care Skip to main content SpringerLink Log in Menu Find a journal Publish …

The use of corticosteroids in the care of critically ill patients has been the subject of
continuous research efforts with discrepant results. In sepsis, several “swings of the …

Importance Severe pulmonary infections, including COVID-19, community-acquired
pneumonia, influenza, andPneumocystispneumonia, are a leading cause of death among …

Community-acquired pneumonia represents the third-highest cause of mortality in
industrialized countries and the first due to infection. Although guidelines for the approach to …

Acute respiratory failure is a complex and heterogenous clinical entity of which there are
multiple etiologies including infection, trauma, and shock. The management of acute …