Genome-scale analyses have allowed us to progress beyond studying gene expression at
the level of individual components of a given process by providing global information about …

Dr. Harris has played a major role in the development of this organism as a model system.
Her previous version of the Chlamydomonas Sourcebook which published in 1989, has …

The nonrandom spatial distribution of chromosomes and genes in the eukaryotic nucleus
has been appreciated for decades, although a detailed understanding of the functional role …

Dnmt1 epigenetically propagates symmetrical CG methylation in many eukaryotes. Their
genomes are typically depleted of CG dinucleotides because of imperfect repair of …

The mechanism of transport of mRNA-protein (mRNP) complexes from transcription sites to
nuclear pores has been the subject of many studies. Using molecular beacons to track …

Although the spatial location of genes within the nucleus has been implicated in their
transcriptional status, little is known about the dynamics of gene location that accompany …

Many proteins of the photosynthesis complexes are encoded by the genome of the
chloroplast and synthesized by bacterium-like ribosomes within this organelle. To determine …

The deadliest form of human malaria is caused by the protozoan parasite Plasmodium
falciparum. The complex life cycle of this parasite is associated with tight transcriptional …

The compartmentalization of eukaryotic cells requires that newly synthesized proteins be
targeted to the compartments in which they function. In chloroplasts, a few thousand proteins …

Eukaryotic cells under stress repress translation and localize these messenger RNAs
(mRNAs) to cytoplasmic RNA granules. We show that specific stress stimuli induce the …